Identity
HGNC
LOCATION
8p22
LOCUSID
ALIAS
EFA6D,EFA6R,HCA67
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 23362
MIM: 614440
HGNC: 19093
Ensembl: ENSG00000156011
Variants:
dbSNP: 23362
ClinVar: 23362
TCGA: ENSG00000156011
COSMIC: PSD3
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Endocytosis | KEGG | ko04144 |
| Endocytosis | KEGG | hsa04144 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35102341 | 2022 | PSD3 downregulation confers protection against fatty liver disease. | 9 |
| 35102341 | 2022 | PSD3 downregulation confers protection against fatty liver disease. | 9 |
| 28237857 | 2017 | Genetic association analysis of polymorphisms in PSD3 gene with obesity, type 2 diabetes, and HDL cholesterol. | 7 |
| 28237857 | 2017 | Genetic association analysis of polymorphisms in PSD3 gene with obesity, type 2 diabetes, and HDL cholesterol. | 7 |
| 25296758 | 2014 | Exchange factor EFA6R requires C-terminal targeting to the plasma membrane to promote cytoskeletal rearrangement through the activation of ADP-ribosylation factor 6 (ARF6). | 14 |
| 25296758 | 2014 | Exchange factor EFA6R requires C-terminal targeting to the plasma membrane to promote cytoskeletal rearrangement through the activation of ADP-ribosylation factor 6 (ARF6). | 14 |
| 20080650 | 2010 | Inherited genetic variant predisposes to aggressive but not indolent prostate cancer. | 57 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 20080650 | 2010 | Inherited genetic variant predisposes to aggressive but not indolent prostate cancer. | 57 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 18649358 | 2008 | Replication of a genome-wide case-control study of esophageal squamous cell carcinoma. | 9 |
| 18649358 | 2008 | Replication of a genome-wide case-control study of esophageal squamous cell carcinoma. | 9 |
| 16270321 | 2005 | Five genes from chromosomal band 8p22 are significantly down-regulated in ovarian carcinoma: N33 and EFA6R have a potential impact on overall survival. | 37 |
| 16270321 | 2005 | Five genes from chromosomal band 8p22 are significantly down-regulated in ovarian carcinoma: N33 and EFA6R have a potential impact on overall survival. | 37 |
Citation
Dessen P
PSD3 (pleckstrin and Sec7 domain containing 3)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43654/psd3
