| Nomenclature |
|---|
| HGNC (Hugo) | PSMC3 9549 |
| Cards |
|---|
| Entrez_Gene (NCBI) | PSMC3 5702 proteasome 26S subunit, ATPase 3 |
| Aliases | TBP1 |
| GeneCards (Weizmann) | PSMC3 |
| Ensembl hg19 (Hinxton) | ENSG00000165916 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000165916 [Gene_View] ENSG00000165916 [Sequence] chr11:47418769-47426473 [Contig_View] PSMC3 [Vega] |
| ICGC DataPortal | ENSG00000165916 |
| TCGA cBioPortal | PSMC3 |
| AceView (NCBI) | PSMC3 |
| Genatlas (Paris) | PSMC3 |
| WikiGenes | 5702 |
| SOURCE (Princeton) | PSMC3 |
| Genetics Home Reference (NIH) | PSMC3 |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | PSMC3 - chr11:47418769-47426473 - 11p11.2 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | PSMC3 - 11p11.2 [Description] (hg19-Feb_2009) |
| GoldenPath | PSMC3 - 11p11.2 [CytoView hg19] PSMC3 - 11p11.2 [CytoView hg38] |
| ImmunoBase | ENSG00000165916 |
| Mapping of homologs : NCBI | PSMC3 [Mapview hg19] PSMC3 [Mapview hg38] |
| OMIM | 186852 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AK222485 AK291896 AK313518 BC008713 BC073165 |
| RefSeq transcript (Entrez) | NM_002804 |
| RefSeq genomic (Entrez) | |
| Consensus coding sequences : CCDS (NCBI) | PSMC3 |
| Cluster EST : Unigene | Hs.250758 [ NCBI ] |
| CGAP (NCI) | Hs.250758 |
| Alternative Splicing Gallery | ENSG00000165916 |
| Gene Expression | PSMC3 [ NCBI-GEO ] PSMC3 [ EBI - ARRAY_EXPRESS ]
PSMC3 [ SEEK ] PSMC3 [ MEM ] |
| Gene Expression Viewer (FireBrowse) | PSMC3 [ Firebrowse - Broad ] |
| SOURCE (Princeton) | Expression in : [Datasets] [Normal Tissue Atlas] [carcinoma Classsification] [NCI60] |
| Genevestigator | Expression in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 5702 |
| GTEX Portal (Tissue expression) | PSMC3 |
| Human Protein Atlas | ENSG00000165916-PSMC3 [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | P17980 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | P17980 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | P17980 |
| Splice isoforms : SwissVar | P17980 |
| PhosPhoSitePlus | P17980 |
| Domaine pattern : Prosite (Expaxy) | AAA (PS00674) |
| Domains : Interpro (EBI) | 26S_Psome_P45-like AAA+_ATPase ATPase_AAA_core ATPase_AAA_CS P-loop_NTPase PSMC3 |
| Domain families : Pfam (Sanger) | AAA (PF00004) |
| Domain families : Pfam (NCBI) | pfam00004 |
| Domain families : Smart (EMBL) | AAA (SM00382) |
| Conserved Domain (NCBI) | PSMC3 |
| DMDM Disease mutations | 5702 |
| Blocks (Seattle) | PSMC3 |
| PDB (RSDB) | 5GJQ 5GJR 5L4G 5LN3 5M32 5T0C 5T0G 5T0H 5T0I 5T0J 5VGZ 5VHF 5VHH 5VHI 5VHJ 5VHM 5VHN 5VHO 5VHP 5VHQ 5VHR 5VHS |
| PDB Europe | 5GJQ 5GJR 5L4G 5LN3 5M32 5T0C 5T0G 5T0H 5T0I 5T0J 5VGZ 5VHF 5VHH 5VHI 5VHJ 5VHM 5VHN 5VHO 5VHP 5VHQ 5VHR 5VHS |
| PDB (PDBSum) | 5GJQ 5GJR 5L4G 5LN3 5M32 5T0C 5T0G 5T0H 5T0I 5T0J 5VGZ 5VHF 5VHH 5VHI 5VHJ 5VHM 5VHN 5VHO 5VHP 5VHQ 5VHR 5VHS |
| PDB (IMB) | 5GJQ 5GJR 5L4G 5LN3 5M32 5T0C 5T0G 5T0H 5T0I 5T0J 5VGZ 5VHF 5VHH 5VHI 5VHJ 5VHM 5VHN 5VHO 5VHP 5VHQ 5VHR 5VHS |
| Structural Biology KnowledgeBase | 5GJQ 5GJR 5L4G 5LN3 5M32 5T0C 5T0G 5T0H 5T0I 5T0J 5VGZ 5VHF 5VHH 5VHI 5VHJ 5VHM 5VHN 5VHO 5VHP 5VHQ 5VHR 5VHS |
| SCOP (Structural Classification of Proteins) | 5GJQ 5GJR 5L4G 5LN3 5M32 5T0C 5T0G 5T0H 5T0I 5T0J 5VGZ 5VHF 5VHH 5VHI 5VHJ 5VHM 5VHN 5VHO 5VHP 5VHQ 5VHR 5VHS |
| CATH (Classification of proteins structures) | 5GJQ 5GJR 5L4G 5LN3 5M32 5T0C 5T0G 5T0H 5T0I 5T0J 5VGZ 5VHF 5VHH 5VHI 5VHJ 5VHM 5VHN 5VHO 5VHP 5VHQ 5VHR 5VHS |
| Superfamily | P17980 |
| Human Protein Atlas [tissue] | ENSG00000165916-PSMC3 [tissue] |
| Peptide Atlas | P17980 |
| HPRD | 01733 |
| IPI | IPI00018398 IPI00979423 IPI00978735 IPI00979951 IPI00978171 IPI00980661 IPI00978915 IPI00982304 IPI00979529 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | P17980 |
| IntAct (EBI) | P17980 |
| FunCoup | ENSG00000165916 |
| BioGRID | PSMC3 |
| STRING (EMBL) | PSMC3 |
| ZODIAC | PSMC3 |
| Ontologies - Pathways |
|---|
| QuickGO | P17980 |
| Ontology : AmiGO | MAPK cascade protein polyubiquitination proteasome complex P-body blastocyst development stimulatory C-type lectin receptor signaling pathway antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent protein binding ATP binding extracellular region nucleus nucleus nucleoplasm cytosol regulation of cellular amino acid metabolic process proteasome regulatory particle, base subcomplex negative regulation of G2/M transition of mitotic cell cycle membrane viral process protein deubiquitination ATPase activity proteasome accessory complex anaphase-promoting complex-dependent catabolic process SCF-dependent proteasomal ubiquitin-dependent protein catabolic process tumor necrosis factor-mediated signaling pathway secretory granule lumen NIK/NF-kappaB signaling Fc-epsilon receptor signaling pathway identical protein binding proteasome-mediated ubiquitin-dependent protein catabolic process neutrophil degranulation regulation of mRNA stability post-translational protein modification modulation by host of viral transcription positive regulation of RNA polymerase II transcriptional preinitiation complex assembly positive regulation of transcription by RNA polymerase II T cell receptor signaling pathway transmembrane transport Wnt signaling pathway, planar cell polarity pathway regulation of transcription from RNA polymerase II promoter in response to hypoxia interleukin-1-mediated signaling pathway negative regulation of canonical Wnt signaling pathway positive regulation of canonical Wnt signaling pathway regulation of mitotic cell cycle phase transition regulation of hematopoietic stem cell differentiation ficolin-1-rich granule lumen |
| Ontology : EGO-EBI | MAPK cascade protein polyubiquitination proteasome complex P-body blastocyst development stimulatory C-type lectin receptor signaling pathway antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent protein binding ATP binding extracellular region nucleus nucleus nucleoplasm cytosol regulation of cellular amino acid metabolic process proteasome regulatory particle, base subcomplex negative regulation of G2/M transition of mitotic cell cycle membrane viral process protein deubiquitination ATPase activity proteasome accessory complex anaphase-promoting complex-dependent catabolic process SCF-dependent proteasomal ubiquitin-dependent protein catabolic process tumor necrosis factor-mediated signaling pathway secretory granule lumen NIK/NF-kappaB signaling Fc-epsilon receptor signaling pathway identical protein binding proteasome-mediated ubiquitin-dependent protein catabolic process neutrophil degranulation regulation of mRNA stability post-translational protein modification modulation by host of viral transcription positive regulation of RNA polymerase II transcriptional preinitiation complex assembly positive regulation of transcription by RNA polymerase II T cell receptor signaling pathway transmembrane transport Wnt signaling pathway, planar cell polarity pathway regulation of transcription from RNA polymerase II promoter in response to hypoxia interleukin-1-mediated signaling pathway negative regulation of canonical Wnt signaling pathway positive regulation of canonical Wnt signaling pathway regulation of mitotic cell cycle phase transition regulation of hematopoietic stem cell differentiation ficolin-1-rich granule lumen |
| Pathways : KEGG | Proteasome Epstein-Barr virus infection |
| NDEx Network | PSMC3 |
| Atlas of Cancer Signalling Network | PSMC3 |
| Wikipedia pathways | PSMC3 |
| Orthology - Evolution |
|---|
| OrthoDB | 5702 |
| GeneTree (enSembl) | ENSG00000165916 |
| Phylogenetic Trees/Animal Genes : TreeFam | PSMC3 |
| HOGENOM | P17980 |
| Homologs : HomoloGene | PSMC3 |
| Homology/Alignments : Family Browser (UCSC) | PSMC3 |
| Gene fusions - Rearrangements |
|---|
| Fusion : Quiver | PSMC3 |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | PSMC3 [hg38] |
| dbSNP Single Nucleotide Polymorphism (NCBI) | PSMC3 |
| dbVar | PSMC3 |
| ClinVar | PSMC3 |
| 1000_Genomes | PSMC3 |
| Exome Variant Server | PSMC3 |
| ExAC (Exome Aggregation Consortium) | ENSG00000165916 |
| GNOMAD Browser | ENSG00000165916 |
| Varsome Browser | PSMC3 |
| Genetic variants : HAPMAP | 5702 |
| Genomic Variants (DGV) | PSMC3 [DGVbeta] |
| DECIPHER | PSMC3 [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | PSMC3 |
| Mutations |
|---|
| ICGC Data Portal | PSMC3 |
| TCGA Data Portal | PSMC3 |
| Broad Tumor Portal | PSMC3 |
| OASIS Portal | PSMC3 [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | PSMC3 [overview] [genome browser] [tissue] [distribution] |
| Somatic Mutations in Cancer : COSMIC3D | PSMC3 |
| Mutations and Diseases : HGMD | PSMC3 |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| BioMuta | search PSMC3 |
| DgiDB (Drug Gene Interaction Database) | PSMC3 |
| DoCM (Curated mutations) | PSMC3 (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | PSMC3 (select a term) |
| intoGen | PSMC3 |
| Cancer3D | PSMC3(select the gene name) |
| Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 186852 |
| Orphanet | |
| DisGeNET | PSMC3 |
| Medgen | PSMC3 |
| Genetic Testing Registry | PSMC3
|
| NextProt | P17980 [Medical] |
| TSGene | 5702 |
| GENETests | PSMC3 |
| Target Validation | PSMC3 |
| Huge Navigator |
PSMC3 [HugePedia] |
| snp3D : Map Gene to Disease | 5702 |
| BioCentury BCIQ | PSMC3 |
| ClinGen | PSMC3 |
| Clinical trials, drugs, therapy |
|---|
| Chemical/Protein Interactions : CTD | 5702 |
| Chemical/Pharm GKB Gene | PA33894 |
| Clinical trial | PSMC3 |
| Miscellaneous |
|---|
| canSAR (ICR) | PSMC3 (select the gene name) |
| DataMed Index | PSMC3 |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 185 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| CoreMine | PSMC3 |
| EVEX | PSMC3 |
| GoPubMed | PSMC3 |
| iHOP | PSMC3 |
