PSORS1C3 (psoriasis susceptibility 1 candidate 3)

2014-11-01  

Identity

HGNC
LOCATION
6p21.33
LOCUSID
ALIAS
NCRNA00196

Other Information

Locus ID:

NCBI: 100130889
MIM: 618690
HGNC: 17203

Variants:

dbSNP: 100130889
ClinVar: 100130889
COSMIC: PSORS1C3

Expression (GTEx)

0
1
2
3
4
5
6
7

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA166120929severe cutaneous adverse reactionsDiseaseClinicalAnnotationassociatedPD21801394
PA444059Epidermal Necrolysis, ToxicDiseaseClinicalAnnotationassociatedPD21801394
PA445738Stevens-Johnson SyndromeDiseaseClinicalAnnotationassociatedPD21801394
PA448320allopurinolChemicalClinicalAnnotationassociatedPD21801394

References

Pubmed IDYearTitleCitations
158489822005HLA-Cw*0602 associates more strongly to psoriasis in the Swedish population than variants of the novel 6p21.3 gene PSORS1C3.13
169654132006Psoriasis vulgaris in Chinese individuals is associated with PSORS1C3 and CDSN genes.13
295891602018HLA-C*06:02-independent, gender-related association of PSORS1C3 and PSORS1C1/CDSN single-nucleotide polymorphisms with risk and severity of psoriasis.3
280454652017Methylomic profiling of cortex samples from completed suicide cases implicates a role for PSORS1C3 in major depression and suicide.0

Citation

Dessen P

PSORS1C3 (psoriasis susceptibility 1 candidate 3)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/72361/psors1c3