Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5732
MIM: 176804
HGNC: 9594
Ensembl: ENSG00000125384
Variants:
dbSNP: 5732
ClinVar: 5732
TCGA: ENSG00000125384
COSMIC: PTGER2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000125384 | ENST00000245457 | P43116 |
| ENSG00000125384 | ENST00000557436 | G3V2Y6 |
Expression (GTEx)
Pathways
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA175 | GNAS | Gene | Pathway | associated | 20938371 | ||
| PA443450 | Asthma | Disease | ClinicalAnnotation | associated | PD | 17496729 | |
| PA448497 | aspirin | Chemical | ClinicalAnnotation | associated | PD | 17496729 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38753641 | 2024 | Impact of Bone Morphogenetic Protein 7 and Prostaglandin receptors on osteoblast healing and organization of collagen. | 0 |
| 38753641 | 2024 | Impact of Bone Morphogenetic Protein 7 and Prostaglandin receptors on osteoblast healing and organization of collagen. | 0 |
| 37232020 | 2023 | Complementary roles of EP2 and EP4 receptors in malignant glioma. | 2 |
| 37796697 | 2023 | N6-methyladenosine Methyltransferase METTL3 Enhances PTGER2 Expression to Increase Ovarian Cancer Stemness and Chemoresistance. | 1 |
| 37232020 | 2023 | Complementary roles of EP2 and EP4 receptors in malignant glioma. | 2 |
| 37796697 | 2023 | N6-methyladenosine Methyltransferase METTL3 Enhances PTGER2 Expression to Increase Ovarian Cancer Stemness and Chemoresistance. | 1 |
| 34822808 | 2022 | Prostaglandin E2 EP receptors in cardiovascular disease: An update. | 13 |
| 34914140 | 2022 | The EP2 agonist, omidenepag, alters the physical stiffness of 3D spheroids prepared from human corneal stroma fibroblasts differently depending on the osmotic pressure. | 1 |
| 35543087 | 2022 | Increased COX-2 after ureter obstruction attenuates fibrosis and is associated with EP(2) receptor upregulation in mouse and human kidney. | 3 |
| 34822808 | 2022 | Prostaglandin E2 EP receptors in cardiovascular disease: An update. | 13 |
| 34914140 | 2022 | The EP2 agonist, omidenepag, alters the physical stiffness of 3D spheroids prepared from human corneal stroma fibroblasts differently depending on the osmotic pressure. | 1 |
| 35543087 | 2022 | Increased COX-2 after ureter obstruction attenuates fibrosis and is associated with EP(2) receptor upregulation in mouse and human kidney. | 3 |
| 33545665 | 2021 | Polymorphisms rs2745557 in PTGS2 and rs2075797 in PTGER2 are associated with the risk of chronic obstructive pulmonary disease development in a Tunisian cohort. | 1 |
| 33786738 | 2021 | The differential functional coupling of phosphodiesterase 4 to human DP and EP2 prostanoid receptors stimulated with PGD(2) or PGE(2). | 1 |
| 34529833 | 2021 | Prostaglandin E(2) directly inhibits the conversion of inducible regulatory T cells through EP2 and EP4 receptors via antagonizing TGF-β signalling. | 4 |
Citation
Dessen P
PTGER2 (prostaglandin E receptor 2)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46566/ptger2
