PTGFRN (prostaglandin F2 receptor inhibitor)

2011-04-01  

Identity

HGNC
LOCATION
1p13.1
LOCUSID
ALIAS
CD315,CD9P-1,EWI-F,FPRP,SMAP-6
FUSION GENES

Other Information

Locus ID:

NCBI: 5738
MIM: 601204
HGNC: 9601
Ensembl: ENSG00000134247

Variants:

dbSNP: 5738
ClinVar: 5738
TCGA: ENSG00000134247
COSMIC: PTGFRN

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000134247ENST00000393203Q9P2B2

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
166906122006EWI-2 and EWI-F link the tetraspanin web to the actin cytoskeleton through their direct association with ezrin-radixin-moesin proteins.76
198502832010Identification of novel candidate genes for treatment response to risperidone and susceptibility for schizophrenia: integrated analysis among pharmacogenomics, mouse expression, and genetic case-control association approaches.27
165375452006Contrasting effects of EWI proteins, integrins, and protein palmitoylation on cell surface CD9 organization.19
174071542007The transferrin receptor and the tetraspanin web molecules CD9, CD81, and CD9P-1 are differentially sorted into exosomes after TPA treatment of K562 cells.19
212064922011CD9P-1 expression correlates with the metastatic status of lung cancer, and a truncated form of CD9P-1, GS-168AT2, inhibits in vivo tumour growth.8
197036042009In situ chemical cross-linking on living cells reveals CD9P-1 cis-oligomer at cell surface.6
179607392007Glycosylation status of the membrane protein CD9P-1.2
313772052019The Ig superfamily protein PTGFRN coordinates survival signaling in glioblastoma multiforme.1

Citation

Dessen P

PTGFRN (prostaglandin F2 receptor inhibitor)

Atlas Genet Cytogenet Oncol Haematol. 2011-04-01

Online version: http://atlasgeneticsoncology.org/gene/52161/ptgfrn