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PTP4A3 (protein tyrosine phosphatase type IVA, member 3)

Identity

Other namesPRL-3
PRL-R
PRL3
HGNC (Hugo) PTP4A3
LocusID (NCBI) 11156
Location 8q24.3
Location_base_pair Starts at 142432007 and ends at 142441620 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)PTP4A3   9636
Entrez_Gene (NCBI)PTP4A3  11156  protein tyrosine phosphatase type IVA, member 3
Cards
GeneCards (Weizmann)PTP4A3
Ensembl (Hinxton)ENSG00000184489 [Gene_View]  chr8:142432007-142441620 [Contig_View]  PTP4A3 [Vega]
AceView (NCBI)PTP4A3
Genatlas (Paris)PTP4A3
SOURCE (Stanford)NM_007079 NM_032611
Genomic and cartography
GoldenPath (UCSC)PTP4A3  -  8q24.3   chr8:142432007-142441620 +  8q24.3   [Description]    (hg19-Feb_2009)
EnsemblPTP4A3 - 8q24.3 [CytoView]
Mapping of homologs : NCBIPTP4A3 [Mapview]
OMIM606449   
Gene and transcription
Genbank (Entrez)AF041434 AI742376 AJ276554 BC003105 BE778111
RefSeq transcript (SRS)NM_007079 NM_032611
RefSeq transcript (Entrez)NM_007079 NM_032611
RefSeq genomic (SRS)AC_000140 NC_000008 NC_018919 NT_008046 NW_001839140 NW_004078037
RefSeq genomic (Entrez)AC_000140 NC_000008 NC_018919 NT_008046 NW_001839140 NW_004078037
Consensus coding sequences : CCDS (NCBI)PTP4A3
Cluster EST : UnigeneHs.43666 [ SRS ] Hs.43666 [ NCBI ]
CGAP (NCI)Hs.43666
Alternative Splicing : Fast-db (Paris)GSHG0033563
Alternative Splicing GalleryENSG00000184489
Gene ExpressionPTP4A3 [ NCBI-GEO ]   PTP4A3 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75365 (SRS) O75365 (Uniprot)
NextProtO75365
With graphics : InterProO75365
Splice isoforms : SwissVarO75365(Swissvar)
Domaine pattern : Prosite (SRS)TYR_PHOSPHATASE_1 (PS00383)    TYR_PHOSPHATASE_2 (PS50056)    TYR_PHOSPHATASE_PTP (PS50055)   
Domaine pattern : Prosite (Expaxy)TYR_PHOSPHATASE_1 (PS00383)    TYR_PHOSPHATASE_2 (PS50056)    TYR_PHOSPHATASE_PTP (PS50055)   
Domains : Interpro (SRS)Tyr/Dual-specificity_Pase    Tyr_Pase_rcpt/non-rcpt   
Domains : Interpro (EBI)Tyr/Dual-specificity_Pase    Tyr_Pase_rcpt/non-rcpt   
Related proteins : CluSTrO75365
Domain families : Pfam (SRS)Y_phosphatase (PF00102)   
Domain families : Pfam (Sanger)Y_phosphatase (PF00102)   
Domain families : Pfam (NCBI)pfam00102   
DMDM11156
Blocks (Seattle)O75365
PDB (SRS)1R6H    1V3A   
PDB (PDBSum)1R6H    1V3A   
PDB (IMB)1R6H    1V3A   
PDB (RSDB)1R6H    1V3A   
Human Protein AtlasENSG00000184489
HPRD05922
IPIIPI00289328   IPI00026647   IPI00217075   IPI00983444   IPI00982778   
Protein Interaction databases
DIP (DOE-UCLA)O75365
IntAct (EBI)O75365
FunCoupENSG00000184489
REACTOMEPTP4A3
Protein Interaction Database11156
BioGRIDPTP4A3
InParanoidO75365
Interologous Interaction database O75365
IntegromeDBPTP4A3
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)PTP4A3
SNP (GeneSNP Utah)PTP4A3
SNP : HGBasePTP4A3
Genetic variants : HAPMAPPTP4A3
Somatic Mutations in Cancer : COSMICPTP4A3 
CONAN: Copy Number AnalysisPTP4A3 
Mutations and Diseases : HGMDPTP4A3
OMIM606449   
GENETests606449   
Disease Genetic AssociationPTP4A3
Huge Navigator PTP4A3 [HugePedia]  PTP4A3 [HugeCancerGEM]
Genomic VariantsPTP4A3  PTP4A3 [DGVbeta]
snp3D : Map Gene to Disease11156
General knowledge
Homologs : HomoloGenePTP4A3
Homology/Alignments : Family Browser (UCSC)PTP4A3
Phylogenetic Trees/Animal Genes : TreeFamPTP4A3
Catalytic activity : Enzyme3.1.3.48 [ Enzyme-Expasy ]   3.1.3.48 [ Enzyme-SRS ]   3.1.3.48 [ IntEnz-EBI ]   3.1.3.48 [ BRENDA ]   3.1.3.48 [ KEGG ]   
Chemical/Protein Interactions : CTD11156
Chemical/Pharm GKB GenePA33979
Clinical trialPTP4A3
Cancer Resource (Charite)ENSG00000184489
Ontology : AmiGOprenylated protein tyrosine phosphatase activity  early endosome  plasma membrane  
Ontology : EGO-EBIprenylated protein tyrosine phosphatase activity  early endosome  plasma membrane  
Other databases
Probes
Litterature
PubMed86 Pubmed reference(s) in Entrez
PubGenePTP4A3
iHOPPTP4A3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:28:17 CEST 2013
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