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PTP4A3 (protein tyrosine phosphatase type IVA, member 3)

Identity

Other namesPRL-3
PRL-R
PRL3
HGNC (Hugo) PTP4A3
LocusID (NCBI) 11156
Location 8q24.3
Location_base_pair Starts at 142431488 and ends at 142442554 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)PTP4A3   9636
Cards
Entrez_Gene (NCBI)PTP4A3  11156  protein tyrosine phosphatase type IVA, member 3
GeneCards (Weizmann)PTP4A3
Ensembl (Hinxton) [Gene_View]  chr8:142431488-142442554 [Contig_View]  PTP4A3 [Vega]
AceView (NCBI)PTP4A3
Genatlas (Paris)PTP4A3
WikiGenes11156
SOURCE (Princeton)NM_007079 NM_032611
Genomic and cartography
GoldenPath (UCSC)PTP4A3  -  8q24.3   chr8:142431488-142442554 +  8q24.3   [Description]    (hg19-Feb_2009)
EnsemblPTP4A3 - 8q24.3 [CytoView]
Mapping of homologs : NCBIPTP4A3 [Mapview]
OMIM606449   
Gene and transcription
Genbank (Entrez)AF041434 AI742376 AJ276554 AK311257 BC003105
RefSeq transcript (Entrez)NM_007079 NM_032611
RefSeq genomic (Entrez)AC_000140 NC_000008 NC_018919 NT_008046 NT_187574 NW_001839140 NW_004929340
Consensus coding sequences : CCDS (NCBI)PTP4A3
Cluster EST : UnigeneHs.744870 [ NCBI ]
CGAP (NCI)Hs.744870
Alternative Splicing : Fast-db (Paris)GSHG0033563
Gene ExpressionPTP4A3 [ NCBI-GEO ]     PTP4A3 [ SEEK ]   PTP4A3 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75365 (Uniprot)
NextProtO75365  [Medical]
With graphics : InterProO75365
Splice isoforms : SwissVarO75365 (Swissvar)
Catalytic activity : Enzyme3.1.3.48 [ Enzyme-Expasy ]   3.1.3.483.1.3.48 [ IntEnz-EBI ]   3.1.3.48 [ BRENDA ]   3.1.3.48 [ KEGG ]   
Domaine pattern : Prosite (Expaxy)TYR_PHOSPHATASE_2 (PS50056)   
Domains : Interpro (EBI)Prot-tyrosine_phosphatase-like    Tyr/Dual-sp_Pase    Tyr_Pase_rcpt/non-rcpt   
Related proteins : CluSTrO75365
Domain families : Pfam (Sanger)Y_phosphatase (PF00102)   
Domain families : Pfam (NCBI)pfam00102   
DMDM Disease mutations11156
Blocks (Seattle)O75365
PDB (SRS)1R6H    1V3A    2MBC   
PDB (PDBSum)1R6H    1V3A    2MBC   
PDB (IMB)1R6H    1V3A    2MBC   
PDB (RSDB)1R6H    1V3A    2MBC   
Peptide AtlasO75365
HPRD05922
IPIIPI00289328   IPI00026647   IPI00217075   IPI00983444   IPI00982778   
Protein Interaction databases
DIP (DOE-UCLA)O75365
IntAct (EBI)O75365
BioGRIDPTP4A3
IntegromeDBPTP4A3
STRING (EMBL)PTP4A3
Ontologies - Pathways
QuickGOO75365
Ontology : AmiGOprenylated protein tyrosine phosphatase activity  early endosome  plasma membrane  peptidyl-tyrosine dephosphorylation  peptidyl-tyrosine dephosphorylation  
Ontology : EGO-EBIprenylated protein tyrosine phosphatase activity  early endosome  plasma membrane  peptidyl-tyrosine dephosphorylation  peptidyl-tyrosine dephosphorylation  
Protein Interaction DatabasePTP4A3
Wikipedia pathwaysPTP4A3
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)PTP4A3
SNP (GeneSNP Utah)PTP4A3
SNP : HGBasePTP4A3
Genetic variants : HAPMAPPTP4A3
1000_GenomesPTP4A3 
CONAN: Copy Number AnalysisPTP4A3 
Somatic Mutations in Cancer : COSMICPTP4A3 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
DECIPHER (Syndromes)8:142431488-142442554
Mutations and Diseases : HGMDPTP4A3
OMIM606449   
MedgenPTP4A3
GENETestsPTP4A3
Disease Genetic AssociationPTP4A3
Huge Navigator PTP4A3 [HugePedia]  PTP4A3 [HugeCancerGEM]
Genomic VariantsPTP4A3  PTP4A3 [DGVbeta]
Exome VariantPTP4A3
dbVarPTP4A3
ClinVarPTP4A3
snp3D : Map Gene to Disease11156
General knowledge
Homologs : HomoloGenePTP4A3
Homology/Alignments : Family Browser (UCSC)PTP4A3
Phylogenetic Trees/Animal Genes : TreeFamPTP4A3
Chemical/Protein Interactions : CTD11156
Chemical/Pharm GKB GenePA33979
Clinical trialPTP4A3
Other databases
Probes
Litterature
PubMed107 Pubmed reference(s) in Entrez
CoreMinePTP4A3
GoPubMedPTP4A3
iHOPPTP4A3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Nov 8 17:51:31 CET 2014

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