PTP4A3 (protein tyrosine phosphatase 4A3)

2003-02-01  

Identity

HGNC
LOCATION
8q24.3
LOCUSID
ALIAS
PRL-3,PRL-R,PRL3
FUSION GENES

Other Information

Locus ID:

NCBI: 11156
MIM: 606449
HGNC: 9636
Ensembl: ENSG00000184489

Variants:

dbSNP: 11156
ClinVar: 11156
TCGA: ENSG00000184489
COSMIC: PTP4A3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000184489ENST00000329397O75365
ENSG00000184489ENST00000349124O75365
ENSG00000184489ENST00000520105O75365
ENSG00000184489ENST00000521578O75365
ENSG00000184489ENST00000523147E5RGR3
ENSG00000184489ENST00000524028E5RFQ4

Expression (GTEx)

0
50
100
150
200
250
300

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
350988692022The phosphatase of regenerating liver-3 protein (PRL-3) promotes glioma cell invasiveness by interacting with β3 -tubulin.1
358171122022The effects of endosulfan on cell migration and invasion in prostate cancer cells via the KCNQ1OT1/miR-137-3p/PTP4A3 axis.1
363368602022The Deubiquitinating Enzyme USP4 Functions as an Oncoprotein in Gastric Cancer and Mediates NF-κB Signaling by Regulating PRL-3 Expression.3
350988692022The phosphatase of regenerating liver-3 protein (PRL-3) promotes glioma cell invasiveness by interacting with β3 -tubulin.1
358171122022The effects of endosulfan on cell migration and invasion in prostate cancer cells via the KCNQ1OT1/miR-137-3p/PTP4A3 axis.1
363368602022The Deubiquitinating Enzyme USP4 Functions as an Oncoprotein in Gastric Cancer and Mediates NF-κB Signaling by Regulating PRL-3 Expression.3
326063182021PRL3 enhances T-cell acute lymphoblastic leukemia growth through suppressing T-cell signaling pathways and apoptosis.9
326165392021Association of PTP4A3 expression and tumour size in functioning pituitary adenoma: a descriptive study.1
331792912021Correlation of PRL3 expression with colorectal cancer progression.4
335663852021Phosphatase of regenerating liver-3 regulates cancer cell metabolism in multiple myeloma.16
340920112021PRL-3 induces a positive signaling circuit between glycolysis and activation of STAT1/2.9
341290572021The phosphatase PRL-3 affects intestinal homeostasis by altering the crypt cell composition.2
342094602021Credentialing and Pharmacologically Targeting PTP4A3 Phosphatase as a Molecular Target for Ovarian Cancer.5
344820232021Rag GTPases suppress PRL-3 degradation and predict poor clinical diagnosis of cancer patients with low PRL-3 mRNA expression.3
346303922021PTP4A3 Is a Prognostic Biomarker Correlated With Immune Infiltrates in Papillary Renal Cell Carcinoma.5

Citation

Dessen P

PTP4A3 (protein tyrosine phosphatase 4A3)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/41908/ptp4a3