Identity
HGNC
LOCATION
2q14.2
LOCUSID
ALIAS
MEG,PTPMEG,PTPMEG1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5775
MIM: 176878
HGNC: 9656
Ensembl: ENSG00000088179
Variants:
dbSNP: 5775
ClinVar: 5775
TCGA: ENSG00000088179
COSMIC: PTPN4
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38630149 | 2024 | circRNA-PTPN4 mediated regulation of FOXO3 and ZO-1 expression: implications for blood-brain barrier integrity and cognitive function in uremic encephalopathy. | 0 |
| 38630149 | 2024 | circRNA-PTPN4 mediated regulation of FOXO3 and ZO-1 expression: implications for blood-brain barrier integrity and cognitive function in uremic encephalopathy. | 0 |
| 37747937 | 2023 | E3 Ubiquitin Ligase MARCH8 Promotes Pancreatic Cancer Growth and Metastasis by Activating STAT3 via Degradation of PTPN4. | 1 |
| 37747937 | 2023 | E3 Ubiquitin Ligase MARCH8 Promotes Pancreatic Cancer Growth and Metastasis by Activating STAT3 via Degradation of PTPN4. | 1 |
| 35089587 | 2022 | Structural and biochemical analysis of the PTPN4 PDZ domain bound to the C-terminal tail of the human papillomavirus E6 oncoprotein. | 1 |
| 36042375 | 2022 | MicroRNA-375 is a therapeutic target for castration-resistant prostate cancer through the PTPN4/STAT3 axis. | 10 |
| 35089587 | 2022 | Structural and biochemical analysis of the PTPN4 PDZ domain bound to the C-terminal tail of the human papillomavirus E6 oncoprotein. | 1 |
| 36042375 | 2022 | MicroRNA-375 is a therapeutic target for castration-resistant prostate cancer through the PTPN4/STAT3 axis. | 10 |
| 31025789 | 2019 | Loss of PTPN4 activates STAT3 to promote the tumor growth in rectal cancer. | 13 |
| 31025789 | 2019 | Loss of PTPN4 activates STAT3 to promote the tumor growth in rectal cancer. | 13 |
| 27923202 | 2017 | Structure-based optimization of salt-bridge network across the complex interface of PTPN4 PDZ domain with its peptide ligands in neuroglioma. | 1 |
| 28801650 | 2017 | Regulation of the Human Phosphatase PTPN4 by the inter-domain linker connecting the PDZ and the phosphatase domains. | 7 |
| 27923202 | 2017 | Structure-based optimization of salt-bridge network across the complex interface of PTPN4 PDZ domain with its peptide ligands in neuroglioma. | 1 |
| 28801650 | 2017 | Regulation of the Human Phosphatase PTPN4 by the inter-domain linker connecting the PDZ and the phosphatase domains. | 7 |
| 27246854 | 2016 | Molecular Basis of the Interaction of the Human Protein Tyrosine Phosphatase Non-receptor Type 4 (PTPN4) with the Mitogen-activated Protein Kinase p38γ. | 16 |
Citation
Dessen P
PTPN4 (protein tyrosine phosphatase non-receptor type 4)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/41919/ptpn4
