PTPRF (protein tyrosine phosphatase receptor type F)

2003-11-01  

Identity

HGNC
LOCATION
1p34.2
LOCUSID
ALIAS
BNAH2,LAR
FUSION GENES

Other Information

Locus ID:

NCBI: 5792
MIM: 179590
HGNC: 9670
Ensembl: ENSG00000142949

Variants:

dbSNP: 5792
ClinVar: 5792
TCGA: ENSG00000142949
COSMIC: PTPRF

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000142949ENST00000359947P10586
ENSG00000142949ENST00000372407H0Y380
ENSG00000142949ENST00000412568H0Y4H1
ENSG00000142949ENST00000414879H0Y7Z9
ENSG00000142949ENST00000429895H0Y6Z7
ENSG00000142949ENST00000437607A2A437
ENSG00000142949ENST00000438120P10586
ENSG00000142949ENST00000617451A2A437

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
Cell adhesion molecules (CAMs)KEGGko04514
Adherens junctionKEGGko04520
Insulin signaling pathwayKEGGko04910
Cell adhesion molecules (CAMs)KEGGhsa04514
Adherens junctionKEGGhsa04520
Insulin signaling pathwayKEGGhsa04910
Neuronal SystemREACTOMER-HSA-112316
Insulin resistanceKEGGhsa04931
SALM protein interactions at the synapsesREACTOMER-HSA-8849932
Protein-protein interactions at synapsesREACTOMER-HSA-6794362

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
349693572022miR-647 inhibits hepatocellular carcinoma cell progression by targeting protein tyrosine phosphatase receptor type F.2
357350102022Cytoneme-like protrusion formation induced by LAR is promoted by receptor dimerization.1
349693572022miR-647 inhibits hepatocellular carcinoma cell progression by targeting protein tyrosine phosphatase receptor type F.2
357350102022Cytoneme-like protrusion formation induced by LAR is promoted by receptor dimerization.1
323550372020Crystal and solution structures of fragments of the human leucocyte common antigen-related protein.6
329733312020Inhibition of protein tyrosine phosphatase receptor type F suppresses Wnt signaling in colorectal cancer.12
323550372020Crystal and solution structures of fragments of the human leucocyte common antigen-related protein.6
329733312020Inhibition of protein tyrosine phosphatase receptor type F suppresses Wnt signaling in colorectal cancer.12
317996662019PPARγ inhibits breast cancer progression by upregulating PTPRF expression.13
317996662019PPARγ inhibits breast cancer progression by upregulating PTPRF expression.13
295702752018Structural Characterization of a Heparan Sulfate Pentamer Interacting with LAR-Ig1-2.7
302175602018CD133-induced TM4SF5 expression promotes sphere growth via recruitment and blocking of protein tyrosine phosphatase receptor type F (PTPRF).9
295702752018Structural Characterization of a Heparan Sulfate Pentamer Interacting with LAR-Ig1-2.7
302175602018CD133-induced TM4SF5 expression promotes sphere growth via recruitment and blocking of protein tyrosine phosphatase receptor type F (PTPRF).9
262910132015PTPRF Expression as a Potential Prognostic/Predictive Marker for Treatment with Erlotinib in Non-Small-Cell Lung Cancer.12

Citation

Dessen P

PTPRF (protein tyrosine phosphatase receptor type F)

Atlas Genet Cytogenet Oncol Haematol. 2003-11-01

Online version: http://atlasgeneticsoncology.org/gene/41929/ptprf