PTPRU (protein tyrosine phosphatase receptor type U)

2003-06-01  

Identity

HGNC
LOCATION
1p35.3
LOCUSID
ALIAS
FMI,PCP-2,PTP,PTP-J,PTP-PI,PTP-RO,PTPPSI,PTPRO,PTPU2,R-PTP-PSI,R-PTP-U,hPTP-J
FUSION GENES

Other Information

Locus ID:

NCBI: 10076
MIM: 602454
HGNC: 9683
Ensembl: ENSG00000060656

Variants:

dbSNP: 10076
ClinVar: 10076
TCGA: ENSG00000060656
COSMIC: PTPRU

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000060656ENST00000345512Q92729
ENSG00000060656ENST00000373779Q92729
ENSG00000060656ENST00000428026Q92729
ENSG00000060656ENST00000460170Q92729

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signaling by SCF-KITREACTOMER-HSA-1433557

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
165746482006Protein-tyrosine phosphatase PCP-2 inhibits beta-catenin signaling and increases E-cadherin-dependent cell adhesion.20
195283532009Decreased nephrin and GLEPP-1, but increased VEGF, Flt-1, and nitrotyrosine, expressions in kidney tissue sections from women with preeclampsia.20
277610232016MicroRNA-574-5p promotes metastasis of non-small cell lung cancer by targeting PTPRU.15
125012152002Physical and functional interaction between receptor-like protein tyrosine phosphatase PCP-2 and beta-catenin.13
248761532014Protein tyrosine phosphatase receptor U (PTPRU) is required for glioma growth and motility.8
165645542006Expression of synaptopodin and GLEPP1 as markers of steroid responsiveness in primary focal segmental glomerulosclerosis.6
253372162014Knockdown of protein tyrosine phosphatase receptor U inhibits growth and motility of gastric cancer cells.4

Citation

Dessen P

PTPRU (protein tyrosine phosphatase receptor type U)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/41940/ptpru