PTTG2 (pituitary tumor-transforming 2)

2003-02-01  

Identity

HGNC
PTTG2
LOCATION
4p14
LOCUSID
10744
ALIAS
-

Other Information

Locus ID:

NCBI: 10744
MIM: 604231
HGNC: 9691
Ensembl: ENSG00000250254

Variants:

dbSNP: 10744
ClinVar: 10744
TCGA: ENSG00000250254
COSMIC: PTTG2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000250254ENST00000504686Q9NZH5

Expression (GTEx)

0
1
2
3
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Cell cycleKEGGko04110
Cell cycleKEGGhsa04110
Oocyte meiosisKEGGko04114
Oocyte meiosisKEGGhsa04114
HTLV-I infectionKEGGko05166
HTLV-I infectionKEGGhsa05166

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
234705372013PTTG2 silencing results in induction of epithelial-to-mesenchymal transition and apoptosis.6
266178032015Pituitary tumor transforming gene PTTG2 induces psoriasis by regulating vimentin and E-cadherin expression.1

Citation

Dessen P

PTTG2 (pituitary tumor-transforming 2)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/41945/pttg2