PXDN (peroxidasin)

2003-02-01  

Identity

HGNC
LOCATION
2p25.3
LOCUSID
ALIAS
ASGD7,COPOA,D2S448,D2S448E,MG50,PRG2,PXN,VPO
FUSION GENES

Other Information

Locus ID:

NCBI: 7837
MIM: 605158
HGNC: 14966
Ensembl: ENSG00000130508

Variants:

dbSNP: 7837
ClinVar: 7837
TCGA: ENSG00000130508
COSMIC: PXDN

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000130508ENST00000252804Q92626
ENSG00000130508ENST00000425171C9J4I9
ENSG00000130508ENST00000433670H7C1W1
ENSG00000130508ENST00000447941H7C300
ENSG00000130508ENST00000453308H7C3W2

Expression (GTEx)

0
50
100
150
200

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
378012862023The role of peroxidasin in solid cancer progression.2
378012862023The role of peroxidasin in solid cancer progression.2
350935882022Peroxidasin Deficiency Re-programs Macrophages Toward Pro-fibrolysis Function and Promotes Collagen Resolution in Liver.9
353170992022Differential DNA methylation analysis of SUMF2, ADAMTS5, and PXDN provides novel insights into colorectal cancer prognosis prediction in Taiwan.3
350935882022Peroxidasin Deficiency Re-programs Macrophages Toward Pro-fibrolysis Function and Promotes Collagen Resolution in Liver.9
353170992022Differential DNA methylation analysis of SUMF2, ADAMTS5, and PXDN provides novel insights into colorectal cancer prognosis prediction in Taiwan.3
328131432021Vascular peroxidase 1 is independently associated with worse kidney function in patients with peripheral artery disease.1
339035912021PXDN reduces autophagic flux in insulin-resistant cardiomyocytes via modulating FoxO1.5
339854102021Novel heterozygous variants in PXDN cause different anterior segment dysgenesis phenotypes in monozygotic twins.3
328131432021Vascular peroxidase 1 is independently associated with worse kidney function in patients with peripheral artery disease.1
339035912021PXDN reduces autophagic flux in insulin-resistant cardiomyocytes via modulating FoxO1.5
339854102021Novel heterozygous variants in PXDN cause different anterior segment dysgenesis phenotypes in monozygotic twins.3
312955572020Monomeric and homotrimeric solution structures of truncated human peroxidasin 1 variants.5
319531332020Reaction of human peroxidasin 1 compound I and compound II with one-electron donors.7
320153782020Novel PXDN biallelic variants in patients with microphthalmia and anterior segment dysgenesis.3

Citation

Dessen P

PXDN (peroxidasin)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/40257/pxdn