RAB11FIP1 (RAB11 family interacting protein 1)

2008-12-01  

Identity

HGNC
LOCATION
8p11.23
LOCUSID
ALIAS
NOEL1A,RCP,rab11-FIP1
FUSION GENES

Other Information

Locus ID:

NCBI: 80223
MIM: 608737
HGNC: 30265
Ensembl: ENSG00000156675

Variants:

dbSNP: 80223
ClinVar: 80223
TCGA: ENSG00000156675
COSMIC: RAB11FIP1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000156675ENST00000287263Q6WKZ4
ENSG00000156675ENST00000330843Q6WKZ4
ENSG00000156675ENST00000522727E7EX40
ENSG00000156675ENST00000524118Q6WKZ4

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45

Pathways

PathwaySourceExternal ID
EndocytosisKEGGko04144
EndocytosisKEGGhsa04144

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
188385562008Rab-coupling protein coordinates recycling of alpha5beta1 integrin and EGFR1 to promote cell migration in 3D microenvironments.143
196207872009RCP is a human breast cancer-promoting gene with Ras-activating function.59
208108862010Rab11 and its effector Rab coupling protein contribute to the trafficking of beta 1 integrins during axon growth in adult dorsal root ganglion neurons and PC12 cells.55
117865382002Rab coupling protein (RCP), a novel Rab4 and Rab11 effector protein.53
151811502004The RCP-Rab11 complex regulates endocytic protein sorting.49
235929922013Rab11-FIP1C and Rab14 direct plasma membrane sorting and particle incorporation of the HIV-1 envelope glycoprotein complex.42
216407642011Cannabinoid receptor 2 undergoes Rab5-mediated internalization and recycles via a Rab11-dependent pathway.33
232839832013Rab11-family interacting proteins define spatially and temporally distinct regions within the dynamic Rab11a-dependent recycling system.30
153555142004Rab coupling protein associates with phagosomes and regulates recycling from the phagosomal compartment.20
160496962005Differential regulation of AQP2 trafficking in endosomes by microtubules and actin filaments.18

Citation

Dessen P

RAB11FIP1 (RAB11 family interacting protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2008-12-01

Online version: http://atlasgeneticsoncology.org/gene/50552/rab11fip1