Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 64284
MIM: 602206
HGNC: 16523
Ensembl: ENSG00000124839
Variants:
dbSNP: 64284
ClinVar: 64284
TCGA: ENSG00000124839
COSMIC: RAB17
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Metabolism of proteins | REACTOME | R-HSA-392499 |
| Post-translational protein modification | REACTOME | R-HSA-597592 |
| RAB geranylgeranylation | REACTOME | R-HSA-8873719 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 31841274 | 2020 | Downregulation of Rab17 promotes cell proliferation and invasion in non-small cell lung cancer through STAT3/HIF-1α/VEGF signaling. | 15 |
| 31959474 | 2020 | ALS2, the small GTPase Rab17-interacting protein, regulates maturation and sorting of Rab17-associated endosomes. | 2 |
| 31841274 | 2020 | Downregulation of Rab17 promotes cell proliferation and invasion in non-small cell lung cancer through STAT3/HIF-1α/VEGF signaling. | 15 |
| 31959474 | 2020 | ALS2, the small GTPase Rab17-interacting protein, regulates maturation and sorting of Rab17-associated endosomes. | 2 |
| 28471261 | 2019 | Rab17 mediates intermixing of phagocytosed apoptotic cells with recycling endosomes. | 12 |
| 28471261 | 2019 | Rab17 mediates intermixing of phagocytosed apoptotic cells with recycling endosomes. | 12 |
| 28005073 | 2016 | Rab17 mediates differential antigen sorting following efferocytosis and phagocytosis. | 24 |
| 28005073 | 2016 | Rab17 mediates differential antigen sorting following efferocytosis and phagocytosis. | 24 |
| 25707355 | 2015 | Rab17 inhibits the tumourigenic properties of hepatocellular carcinomas via the Erk pathway. | 12 |
| 26191189 | 2015 | Down-regulation of Rab17 promotes tumourigenic properties of hepatocellular carcinoma cells via Erk pathway. | 8 |
| 25707355 | 2015 | Rab17 inhibits the tumourigenic properties of hepatocellular carcinomas via the Erk pathway. | 12 |
| 26191189 | 2015 | Down-regulation of Rab17 promotes tumourigenic properties of hepatocellular carcinoma cells via Erk pathway. | 8 |
| 25052408 | 2014 | Rab17-mediated recycling endosomes contribute to autophagosome formation in response to Group A Streptococcus invasion. | 21 |
| 25052408 | 2014 | Rab17-mediated recycling endosomes contribute to autophagosome formation in response to Group A Streptococcus invasion. | 21 |
| 22328529 | 2012 | ERK2 drives tumour cell migration in three-dimensional microenvironments by suppressing expression of Rab17 and liprin-β2. | 40 |
Citation
Dessen P
RAB17 (RAB17, member RAS oncogene family)
Atlas Genet Cytogenet Oncol Haematol. 2003-12-01
Online version: http://atlasgeneticsoncology.org/gene/41960/rab17
