RAB23 (RAB23, member RAS oncogene family)

2003-12-01  

Identity

HGNC
LOCATION
6p12.1
LOCUSID
ALIAS
HSPC137
FUSION GENES

Other Information

Locus ID:

NCBI: 51715
MIM: 606144
HGNC: 14263
Ensembl: ENSG00000112210

Variants:

dbSNP: 51715
ClinVar: 51715
TCGA: ENSG00000112210
COSMIC: RAB23

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000112210ENST00000317483Q9ULC3
ENSG00000112210ENST00000317483A0A024RD41
ENSG00000112210ENST00000468148Q9ULC3
ENSG00000112210ENST00000468148A0A024RD41

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
RAB geranylgeranylationREACTOMER-HSA-8873719

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
378843512024Downregulation of Rab23 inhibits hepatocellular carcinoma by repressing SHH signaling pathway.2
378843512024Downregulation of Rab23 inhibits hepatocellular carcinoma by repressing SHH signaling pathway.2
380935942023Biomarker of Pulmonary Inflammatory Response in LUAD: miR-584-5p Targets RAB23 to Suppress Inflammation Induced by LPS in A549 Cells.0
380935942023Biomarker of Pulmonary Inflammatory Response in LUAD: miR-584-5p Targets RAB23 to Suppress Inflammation Induced by LPS in A549 Cells.0
347489962022Expansion of the phenotypic and mutational spectrum of Carpenter syndrome.4
347489962022Expansion of the phenotypic and mutational spectrum of Carpenter syndrome.4
328562882021miR-597-3p inhibits invasion and migration of thyroid carcinoma SW579 cells by targeting RAB23.3
342785062021miR‑367‑3p downregulates Rab23 expression and inhibits Hedgehog signaling resulting in the inhibition of the proliferation, migration, and invasion of prostate cancer cells.4
328562882021miR-597-3p inhibits invasion and migration of thyroid carcinoma SW579 cells by targeting RAB23.3
342785062021miR‑367‑3p downregulates Rab23 expression and inhibits Hedgehog signaling resulting in the inhibition of the proliferation, migration, and invasion of prostate cancer cells.4
301913772020Rab23 Promotes Hepatocellular Carcinoma Cell Migration Via Rac1/TGF-β Signaling.12
316358042020lncRNA OSER1-AS1 acts as a ceRNA to promote tumorigenesis in hepatocellular carcinoma by regulating miR-372-3p/Rab23 axis.15
301913772020Rab23 Promotes Hepatocellular Carcinoma Cell Migration Via Rac1/TGF-β Signaling.12
316358042020lncRNA OSER1-AS1 acts as a ceRNA to promote tumorigenesis in hepatocellular carcinoma by regulating miR-372-3p/Rab23 axis.15
314659352019Small GTPases in hedgehog signalling: emerging insights into the disease mechanisms of Rab23-mediated and Arl13b-mediated ciliopathies.9

Citation

Dessen P

RAB23 (RAB23, member RAS oncogene family)

Atlas Genet Cytogenet Oncol Haematol. 2003-12-01

Online version: http://atlasgeneticsoncology.org/gene/41968/rab23