RAB34 (RAB34, member RAS oncogene family)

2003-12-01  

Identity

HGNC
LOCATION
17q11.2
LOCUSID
ALIAS
NARR,RAB39,RAH

Other Information

Locus ID:

NCBI: 83871
MIM: 610917
HGNC: 16519
Ensembl: ENSG00000109113

Variants:

dbSNP: 83871
ClinVar: 83871
TCGA: ENSG00000109113
COSMIC: RAB34

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000109113ENST00000301043Q9BZG1
ENSG00000109113ENST00000301043A0A024QZ68
ENSG00000109113ENST00000353676C9JBG0
ENSG00000109113ENST00000395243A0A1C7CYW6
ENSG00000109113ENST00000395245Q9BZG1
ENSG00000109113ENST00000395245A0A024QZ68
ENSG00000109113ENST00000412625C9JBG0
ENSG00000109113ENST00000415040Q9BZG1
ENSG00000109113ENST00000419712K7EIF2
ENSG00000109113ENST00000422279H7C0Y7
ENSG00000109113ENST00000430132C9JY26
ENSG00000109113ENST00000436730Q9BZG1
ENSG00000109113ENST00000436730A0A024QZ68
ENSG00000109113ENST00000450529Q9BZG1
ENSG00000109113ENST00000453384E7ES60
ENSG00000109113ENST00000580843K7EJW7
ENSG00000109113ENST00000582934V9GY61
ENSG00000109113ENST00000583538J3QLC6
ENSG00000109113ENST00000625712Q96PJ7
ENSG00000109113ENST00000636154P0DI83
ENSG00000109113ENST00000636513A0A1B0GWB1
ENSG00000109113ENST00000636534A0A1B0GVI6
ENSG00000109113ENST00000636772A0A1B0GTQ2

Expression (GTEx)

0
50
100
150
200

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
RAB geranylgeranylationREACTOMER-HSA-8873719

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
180057332007Coxsackievirus entry across epithelial tight junctions requires occludin and the small GTPases Rab34 and Rab5.107
178817362007Golgi-bound Rab34 is a novel member of the secretory pathway.21
199613602010Rab36 regulates the spatial distribution of late endosomes and lysosomes through a similar mechanism to Rab34.17
159966372005The Rab-interacting lysosomal protein, a Rab7 and Rab34 effector, is capable of self-interaction.16
161389002005Diacylglycerol-activated Hmunc13 serves as an effector of the GTPase Rab34.11
255015062015RAB34 was a progression- and prognosis-associated biomarker in gliomas.9
296227942018Rab34 regulates adhesion, migration, and invasion of breast cancer cells.5
196410952009Rab34 and its effector munc13-2 constitute a new pathway modulating protein secretion in the cellular response to hyperglycemia.4
215865862011Identification and characterization of a novel ubiquitous nucleolar protein 'NARR' encoded by a gene overlapping the rab34 oncogene.4
238719332013Spatial distribution of phagolysosomes is independent of the regulation of lysosome position by Rab34.4

Citation

Dessen P

RAB34 (RAB34, member RAS oncogene family)

Atlas Genet Cytogenet Oncol Haematol. 2003-12-01

Online version: http://atlasgeneticsoncology.org/gene/41982/rab34