RAB39A (RAB39A, member RAS oncogene family)

2011-11-01 Affiliation

Identity

HGNC

RAB39A

LOCATION

11q22.3

LOCUSID

54734

ALIAS

RAB39

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 54734
HGNC: 16521
Ensembl: ENSG00000179331

Variants:

dbSNP: 54734
ClinVar: 54734
TCGA: ENSG00000179331
COSMIC: RAB39A

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000179331	ENST00000320578	Q14964

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Metabolism of proteins	REACTOME	R-HSA-392499
Post-translational protein modification	REACTOME	R-HSA-597592
Vesicle-mediated transport	REACTOME	R-HSA-5653656
Membrane Trafficking	REACTOME	R-HSA-199991
Intra-Golgi and retrograde Golgi-to-ER traffic	REACTOME	R-HSA-6811442
Intra-Golgi traffic	REACTOME	R-HSA-6811438
RAB GEFs exchange GTP for GDP on RABs	REACTOME	R-HSA-8876198
RAB geranylgeranylation	REACTOME	R-HSA-8873719

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
20379614	2010	Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.	62
19833722	2009	Rab39a binds caspase-1 and is required for caspase-1-dependent interleukin-1beta secretion.	22
26163492	2015	The late endocytic Rab39a GTPase regulates the interaction between multivesicular bodies and chlamydial inclusions.	14
27494456	2017	C9ORF72 is a GDP/GTP exchange factor for Rab8 and Rab39 and regulates autophagy.	13
29648608	2018	RAB39A: a Rab small GTPase with a prominent role in cancer stemness.	2

Citation

Dessen P

RAB39A (RAB39A, member RAS oncogene family)

Atlas Genet Cytogenet Oncol Haematol. 2011-11-01

Online version: http://atlasgeneticsoncology.org/gene/52497/rab39a