Identity
HGNC
LOCATION
3q21.3
LOCUSID
ALIAS
CMT2B,PRO2706,RAB7
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7879
MIM: 602298
HGNC: 9788
Ensembl: ENSG00000075785
Variants:
dbSNP: 7879
ClinVar: 7879
TCGA: ENSG00000075785
COSMIC: RAB7A
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38593125 | 2024 | Rab7-dependent regulation of goblet cell protein CLCA1 modulates gastrointestinal homeostasis. | 0 |
| 38728007 | 2024 | A RAB7A phosphoswitch coordinates Rubicon Homology protein regulation of Parkin-dependent mitophagy. | 1 |
| 38593125 | 2024 | Rab7-dependent regulation of goblet cell protein CLCA1 modulates gastrointestinal homeostasis. | 0 |
| 38728007 | 2024 | A RAB7A phosphoswitch coordinates Rubicon Homology protein regulation of Parkin-dependent mitophagy. | 1 |
| 37044053 | 2023 | Lipophagy-related gene RAB7A is involved in immune regulation and malignant progression in hepatocellular carcinoma. | 4 |
| 37087591 | 2023 | [Silencing SIRT1 reduces 5-fluorouracil resistance of cholangiocarcinoma cells by inhibiting the FOXO1/Rab7 autophagy pathway]. | 1 |
| 37044053 | 2023 | Lipophagy-related gene RAB7A is involved in immune regulation and malignant progression in hepatocellular carcinoma. | 4 |
| 37087591 | 2023 | [Silencing SIRT1 reduces 5-fluorouracil resistance of cholangiocarcinoma cells by inhibiting the FOXO1/Rab7 autophagy pathway]. | 1 |
| 35637478 | 2022 | Polarized α-synuclein trafficking and transcytosis across brain endothelial cells via Rab7-decorated carriers. | 12 |
| 35887194 | 2022 | Membrane Targeting and GTPase Activity of Rab7 Are Required for Its Ubiquitination by RNF167. | 1 |
| 35637478 | 2022 | Polarized α-synuclein trafficking and transcytosis across brain endothelial cells via Rab7-decorated carriers. | 12 |
| 35887194 | 2022 | Membrane Targeting and GTPase Activity of Rab7 Are Required for Its Ubiquitination by RNF167. | 1 |
| 32280996 | 2021 | Alteration of the late endocytic pathway in Charcot-Marie-Tooth type 2B disease. | 23 |
| 32949647 | 2021 | IKKβ activation promotes amphisome formation and extracellular vesicle secretion in tumor cells. | 13 |
| 33846303 | 2021 | TRIM39 deficiency inhibits tumor progression and autophagic flux in colorectal cancer via suppressing the activity of Rab7. | 12 |
Citation
Dessen P
RAB7A (RAB7A, member RAS oncogene family)
Atlas Genet Cytogenet Oncol Haematol. 2003-11-01
Online version: http://atlasgeneticsoncology.org/gene/42007/rab7a
