RAB7B (RAB7B, member RAS oncogene family)

2003-12-01  

Identity

HGNC
LOCATION
1q32.1
LOCUSID
ALIAS
RAB7

Other Information

Locus ID:

NCBI: 338382
HGNC: 30513
Ensembl: ENSG00000276600

Variants:

dbSNP: 338382
ClinVar: 338382
TCGA: ENSG00000276600
COSMIC: RAB7B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000276600ENST00000617070Q96AH8
ENSG00000276600ENST00000617991Q96AH8
ENSG00000276600ENST00000622969A0A096LPF0
ENSG00000276600ENST00000623597Q96AH8
ENSG00000276600ENST00000623893A0A096LP44

Expression (GTEx)

0
5
10
15
20
25
30
35

Pathways

PathwaySourceExternal ID
Autophagy - animalKEGGko04140
Autophagy - animalKEGGhsa04140
PhagosomeKEGGko04145
PhagosomeKEGGhsa04145
AmoebiasisKEGGko05146
AmoebiasisKEGGhsa05146
Salmonella infectionKEGGko05132
Salmonella infectionKEGGhsa05132
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
RAB GEFs exchange GTP for GDP on RABsREACTOMER-HSA-8876198
TBC/RABGAPsREACTOMER-HSA-8854214
RAB geranylgeranylationREACTOMER-HSA-8873719
Mitophagy - animalKEGGko04137
Mitophagy - animalKEGGhsa04137

References

Pubmed IDYearTitleCitations
233455142013Identification of a role for the trans-Golgi network in human papillomavirus 16 pseudovirus infection.64
259965262015Trichuris suis soluble products induce Rab7b expression and limit TLR4 responses in human dendritic cells.12
301115802018TBC1D5 controls the GTPase cycle of Rab7b.8
288355452017Rab7b modulates autophagic flux by interacting with Atg4B.5
209535742011Small Rab GTPase Rab7b promotes megakaryocytic differentiation by enhancing IL-6 production and STAT3-GATA-1 association.4
203750622010Rab7b controls trafficking from endosomes to the TGN.0
227087382012Dynamics of Rab7b-dependent transport of sorting receptors.0

Citation

Dessen P

RAB7B (RAB7B, member RAS oncogene family)

Atlas Genet Cytogenet Oncol Haematol. 2003-12-01

Online version: http://atlasgeneticsoncology.org/gene/41357/rab7b