RABAC1 (Rab acceptor 1)

2007-02-01  

Identity

HGNC
LOCATION
19q13.2
LOCUSID
ALIAS
PRA1,PRAF1,YIP3

Other Information

Locus ID:

NCBI: 10567
MIM: 604925
HGNC: 9794
Ensembl: ENSG00000105404

Variants:

dbSNP: 10567
ClinVar: 10567
TCGA: ENSG00000105404
COSMIC: RABAC1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000105404ENST00000222008Q9UI14
ENSG00000105404ENST00000600292M0R1H9
ENSG00000105404ENST00000601028M0QXH1
ENSG00000105404ENST00000601078M0QXU8
ENSG00000105404ENST00000601891M0R3D4

Expression (GTEx)

0
100
200
300
400
500
600

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
145744142003Yip3 catalyses the dissociation of endosomal Rab-GDI complexes.85
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
169175022006PRA1 promotes the intracellular trafficking and NF-kappaB signaling of EBV latent membrane protein 1.19
217982442011Human α-synuclein modulates vesicle trafficking through its interaction with prenylated Rab acceptor protein 1.14
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.11
230686072012NDRG2 and PRA1 interact and synergistically inhibit T-cell factor/β-catenin signaling.6
205924222011Proteome-wide dysregulation by PRA1 depletion delineates a role of PRA1 in lipid transport and cell migration.5
169305462006Prenylated Rab acceptor 1 (PRA1) inhibits TCF/beta-catenin signaling by binding to beta-catenin.4

Citation

Dessen P

RABAC1 (Rab acceptor 1)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46483/rabac1