RABL6 (RAB, member RAS oncogene family like 6)

2008-03-01  

Identity

HGNC
LOCATION
9q34.3
LOCUSID
ALIAS
C9orf86,PARF,RBEL1,pp8875
FUSION GENES

Other Information

Locus ID:

NCBI: 55684
MIM: 610615
HGNC: 24703
Ensembl: ENSG00000196642

Variants:

dbSNP: 55684
ClinVar: 55684
TCGA: ENSG00000196642
COSMIC: RABL6

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000196642ENST00000311502Q3YEC7
ENSG00000196642ENST00000357466Q3YEC7
ENSG00000196642ENST00000371663Q3YEC7
ENSG00000196642ENST00000371671Q3YEC7
ENSG00000196642ENST00000436380H0Y7H6
ENSG00000196642ENST00000464941G3V154
ENSG00000196642ENST00000484471F2Z2T0
ENSG00000196642ENST00000629216G3V154

Expression (GTEx)

0
50
100
150

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
342963782022CircTMC5 promotes gastric cancer progression and metastasis by targeting miR-361-3p/RABL6.9
342963782022CircTMC5 promotes gastric cancer progression and metastasis by targeting miR-361-3p/RABL6.9
340652042021RABL6A Regulates Schwann Cell Senescence in an RB1-Dependent Manner.6
340652042021RABL6A Regulates Schwann Cell Senescence in an RB1-Dependent Manner.6
320863422020RABL6A Is an Essential Driver of MPNSTs that Negatively Regulates the RB1 Pathway and Sensitizes Tumor Cells to CDK4/6 Inhibitors.23
326003592020High expression of RABL6 promotes cell proliferation and predicts poor prognosis in esophageal squamous cell carcinoma.5
320863422020RABL6A Is an Essential Driver of MPNSTs that Negatively Regulates the RB1 Pathway and Sensitizes Tumor Cells to CDK4/6 Inhibitors.23
326003592020High expression of RABL6 promotes cell proliferation and predicts poor prognosis in esophageal squamous cell carcinoma.5
307211562019RABL6A inhibits tumor-suppressive PP2A/AKT signaling to drive pancreatic neuroendocrine tumor growth.20
307211562019RABL6A inhibits tumor-suppressive PP2A/AKT signaling to drive pancreatic neuroendocrine tumor growth.20
266763802016RBEL1 is required for osteosarcoma cell proliferation via inhibiting retinoblastoma 1.15
266763802016RBEL1 is required for osteosarcoma cell proliferation via inhibiting retinoblastoma 1.15
252730892014RABL6A promotes G1-S phase progression and pancreatic neuroendocrine tumor cell proliferation in an Rb1-dependent manner.26
252730892014RABL6A promotes G1-S phase progression and pancreatic neuroendocrine tumor cell proliferation in an Rb1-dependent manner.26
235725122013Negative regulation of p53 by Ras superfamily protein RBEL1A.19

Citation

Dessen P

RABL6 (RAB, member RAS oncogene family like 6)

Atlas Genet Cytogenet Oncol Haematol. 2008-03-01

Online version: http://atlasgeneticsoncology.org/gene/50069/rabl6