RAET1G (retinoic acid early transcript 1G)

2015-08-01  

Identity

HGNC
LOCATION
6q25.1
LOCUSID
ALIAS
ULBP5

Other Information

Locus ID:

NCBI: 353091
MIM: 609244
HGNC: 16795
Ensembl: ENSG00000203722

Variants:

dbSNP: 353091
ClinVar: 353091
TCGA: ENSG00000203722
COSMIC: RAET1G

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000203722ENST00000367360Q6H3X3
ENSG00000203722ENST00000367361Q6H3X3
ENSG00000203722ENST00000479265C9JAK3

Expression (GTEx)

0
5
10
15
20

Pathways

PathwaySourceExternal ID
Natural killer cell mediated cytotoxicityKEGGko04650
Natural killer cell mediated cytotoxicityKEGGhsa04650
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Post-translational modification: synthesis of GPI-anchored proteinsREACTOMER-HSA-163125

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
152406962004Two human ULBP/RAET1 molecules with transmembrane regions are ligands for NKG2D.51
252126042014Human anaplastic thyroid carcinoma cells are sensitive to NK cell-mediated lysis via ULBP2/5/6 and chemoattract NK cells.16
196882092009Polymorphisms of NKG2D ligands: diverse RAET1/ULBP genes in northeastern Thais.8
202196102010Single nucleotide polymorphism analysis of the NKG2D ligand cluster on the long arm of chromosome 6: Extensive polymorphisms and evidence of diversity between human populations.7
194249702009Differential NKG2D binding to highly related human NKG2D ligands ULBP2 and RAET1G is determined by a single amino acid in the alpha2 domain.6
192239742009Cellular expression, trafficking, and function of two isoforms of human ULBP5/RAET1G.0
203049222010Post-translational modification of the NKG2D ligand RAET1G leads to cell surface expression of a glycosylphosphatidylinositol-linked isoform.0

Citation

Dessen P

RAET1G (retinoic acid early transcript 1G)

Atlas Genet Cytogenet Oncol Haematol. 2015-08-01

Online version: http://atlasgeneticsoncology.org/gene/55317/raet1g