RBM10 (RNA binding motif protein 10)

2007-02-01  

Identity

HGNC
LOCATION
Xp11.3
LOCUSID
ALIAS
DXS8237E,GPATC9,GPATCH9,S1-1,TARPS,ZRANB5
FUSION GENES

Other Information

Locus ID:

NCBI: 8241
MIM: 300080
HGNC: 9896
Ensembl: ENSG00000182872

Variants:

dbSNP: 8241
ClinVar: 8241
TCGA: ENSG00000182872
COSMIC: RBM10

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000182872ENST00000329236P98175
ENSG00000182872ENST00000345781P98175
ENSG00000182872ENST00000377604P98175
ENSG00000182872ENST00000377604A0A0S2Z4W4
ENSG00000182872ENST00000628161P98175
ENSG00000182872ENST00000628161A0A0S2Z4X1

Expression (GTEx)

0
50
100
150

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
243321782013RBM5, 6, and 10 differentially regulate NUMB alternative splicing to control cancer cell proliferation.98
204511692010Massively parallel sequencing of exons on the X chromosome identifies RBM10 as the gene that causes a syndromic form of cleft palate.56
240001532013Integrative analysis revealed the molecular mechanism underlying RBM10-mediated splicing regulation.32
268535602016Tumor suppressor properties of the splicing regulatory factor RBM10.29
245305242014RBM10 regulates alternative splicing.24
286342822017Genomic Alterations in Fatal Forms of Non-Anaplastic Thyroid Cancer: Identification of MED12 and RBM10 as Novel Thyroid Cancer Genes Associated with Tumor Virulence.20
165527542006Positive correlation between the expression of X-chromosome RBM genes (RBMX, RBM3, RBM10) and the proapoptotic Bax gene in human breast cancer.18
280915942017Functional analysis reveals that RBM10 mutations contribute to lung adenocarcinoma pathogenesis by deregulating splicing.14
282966772017RBM10-TFE3 Renal Cell Carcinoma: A Potential Diagnostic Pitfall Due to Cryptic Intrachromosomal Xp11.2 Inversion Resulting in False-negative TFE3 FISH.14
283794422017An RRM-ZnF RNA recognition module targets RBM10 to exonic sequences to promote exon exclusion.8

Citation

Dessen P

RBM10 (RNA binding motif protein 10)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45786/rbm10