RBM24 (RNA binding motif protein 24)

2014-04-01  

Identity

HGNC
RBM24
LOCATION
6p22.3
LOCUSID
221662
ALIAS
RNPC6,dJ259A10.1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 221662
MIM: 617603
HGNC: 21539
Ensembl: ENSG00000112183

Variants:

dbSNP: 221662
ClinVar: 221662
TCGA: ENSG00000112183
COSMIC: RBM24

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000112183ENST00000318204Q9BX46
ENSG00000112183ENST00000379052Q9BX46
ENSG00000112183ENST00000379052A8KAI7
ENSG00000112183ENST00000425446Q9BX46
ENSG00000112183ENST00000503965H0Y8S7
ENSG00000112183ENST00000509686H0YA61

Expression (GTEx)

0
50
100
150
200
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
198178772009RNA-binding proteins Rbm38 and Rbm24 regulate myogenic differentiation via p21-dependent and -independent regulatory pathways.30
243569692014Rbm24, an RNA-binding protein and a target of p53, regulates p21 expression via mRNA stability.21
275847912016RBM24 suppresses cancer progression by upregulating miR-25 to target MALAT1 in nasopharyngeal carcinoma.21
243756452014RNA-binding protein RBM24 regulates p63 expression via mRNA stability.16
268447002016MicroRNA-222 regulates muscle alternative splicing through Rbm24 during differentiation of skeletal muscle cells.15
269901062016Rbm24 Regulates Alternative Splicing Switch in Embryonic Stem Cell Cardiac Lineage Differentiation.14
285924612017RBM24 promotes U1 snRNP recognition of the mutated 5' splice site in the IKBKAP gene of familial dysautonomia.7
293802052018RNA binding protein 24 regulates the translation and replication of hepatitis C virus.4
297604152018RBM24 stabilizes hepatitis B virus pregenomic RNA but inhibits core protein translation by targeting the terminal redundancy sequence.4
291041632018Global profiling of Rbm24 bound RNAs uncovers a multi-tasking RNA binding protein.2

Citation

Dessen P

RBM24 (RNA binding motif protein 24)

Atlas Genet Cytogenet Oncol Haematol. 2014-04-01

Online version: http://atlasgeneticsoncology.org/gene/53877/rbm24