RBM25 (RNA binding motif protein 25)

2014-11-01  

Identity

HGNC
LOCATION
14q24.2
LOCUSID
ALIAS
NET52,RED120,RNPC7,S164,Snu71,fSAP94
FUSION GENES

Other Information

Locus ID:

NCBI: 58517
MIM: 612427
HGNC: 23244
Ensembl: ENSG00000119707

Variants:

dbSNP: 58517
ClinVar: 58517
TCGA: ENSG00000119707
COSMIC: RBM25

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000119707ENST00000261973P49756
ENSG00000119707ENST00000525161E9PSE8
ENSG00000119707ENST00000525321P49756
ENSG00000119707ENST00000526754P49756
ENSG00000119707ENST00000527432P49756
ENSG00000119707ENST00000528081P49756
ENSG00000119707ENST00000531500E9PQU5
ENSG00000119707ENST00000532192H0YE46

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100

Pathways

PathwaySourceExternal ID
SpliceosomeKEGGko03040
SpliceosomeKEGGhsa03040

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
186630002008Novel splicing factor RBM25 modulates Bcl-x pre-mRNA 5' splice site selection.52
218599732011Role of RBM25/LUC7L3 in abnormal cardiac sodium channel splicing regulation in human heart failure.31
305318342019Dysregulation of p53-RBM25-mediated circAMOTL1L biogenesis contributes to prostate cancer progression through the circAMOTL1L-miR-193a-5p-Pcdha pathway.15
175609982007Identification and characterization of RED120: a conserved PWI domain protein with links to splicing and 3'-end formation.9
286557592017RBM25 is a global splicing factor promoting inclusion of alternatively spliced exons and is itself regulated by lysine mono-methylation.5
231902622013Crystal structure and functional characterization of the human RBM25 PWI domain and its flanking basic region.3
306355672019The splicing factor RBM25 controls MYC activity in acute myeloid leukemia.1

Citation

Dessen P

RBM25 (RNA binding motif protein 25)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/72518/rbm25