RBM38 (RNA binding motif protein 38)

2012-05-01  

Identity

HGNC
LOCATION
20q13.31
LOCUSID
ALIAS
HSRNASEB,RNPC1,SEB4B,SEB4D,dJ800J21.2
FUSION GENES

Other Information

Locus ID:

NCBI: 55544
MIM: 612428
HGNC: 15818
Ensembl: ENSG00000132819

Variants:

dbSNP: 55544
ClinVar: 55544
TCGA: ENSG00000132819
COSMIC: RBM38

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000132819ENST00000342690E9PSF1
ENSG00000132819ENST00000344785F6VZ39
ENSG00000132819ENST00000356208Q9H0Z9
ENSG00000132819ENST00000371219A6NG75
ENSG00000132819ENST00000440234Q9H0Z9

Expression (GTEx)

0
50
100
150
200
250

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
170506752006RNPC1, an RNA-binding protein and a target of the p53 family, is required for maintaining the stability of the basal and stress-induced p21 transcript.64
246630812014Long non-coding RNA HOTAIR promotes cell migration and invasion via down-regulation of RNA binding motif protein 38 in hepatocellular carcinoma cells.57
217648552011Translational repression of p53 by RNPC1, a p53 target overexpressed in lymphomas.53
220275932011Selective inhibition of microRNA accessibility by RBM38 is required for p53 activity.49
204579412010RNPC1, an RNA-binding protein and a target of the p53 family, regulates p63 expression through mRNA stability.36
198178772009RNA-binding proteins Rbm38 and Rbm24 regulate myogenic differentiation via p21-dependent and -independent regulatory pathways.30
225089832012p73 expression is regulated by RNPC1, a target of the p53 family, via mRNA stability.29
227107202013MDM2 expression is repressed by the RNA-binding protein RNPC1 via mRNA stability.24
241428752013Glycogen synthase kinase 3 promotes p53 mRNA translation via phosphorylation of RNPC1.23
223714952012The RNA-binding protein RNPC1 stabilizes the mRNA encoding the RNA-binding protein HuR and cooperates with HuR to suppress cell proliferation.22

Citation

Dessen P

RBM38 (RNA binding motif protein 38)

Atlas Genet Cytogenet Oncol Haematol. 2012-05-01

Online version: http://atlasgeneticsoncology.org/gene/52714/rbm38