RBM7 (RNA binding motif protein 7)

2014-11-01  

Identity

HGNC
RBM7
LOCATION
11q23.2
LOCUSID
10179
ALIAS
-

Other Information

Locus ID:

NCBI: 10179
MIM: 612413
HGNC: 9904
Ensembl: ENSG00000076053

Variants:

dbSNP: 10179
ClinVar: 10179
TCGA: ENSG00000076053
COSMIC: RBM7

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000076053ENST00000375490J3KPD3
ENSG00000076053ENST00000540163Q9Y580
ENSG00000076053ENST00000541475F5GXV8
ENSG00000076053ENST00000542140F5H606
ENSG00000076053ENST00000544313F5H674
ENSG00000076053ENST00000544582F5GY08
ENSG00000076053ENST00000545678G3V1T9
ENSG00000076053ENST00000624815G3V1T9

Expression (GTEx)

0
5
10
15
20
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
279053982016Structure of the RBM7-ZCCHC8 core of the NEXT complex reveals connections to splicing factors.16
255251522015p38MAPK/MK2-mediated phosphorylation of RBM7 regulates the human nuclear exosome targeting complex.13
271931682016Altered RNA metabolism due to a homozygous RBM7 mutation in a patient with spinal motor neuropathy.12
308243722019P-TEFb Activation by RBM7 Shapes a Pro-survival Transcriptional Response to Genotoxic Stress.3
271398322016RRM domain of human RBM7: purification, crystallization and structure determination.0

Citation

Dessen P

RBM7 (RNA binding motif protein 7)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/72533/rbm7