RBMX (RNA binding motif protein X-linked)

2007-02-01  

Identity

HGNC
RBMX
LOCATION
Xq26.3
LOCUSID
27316
ALIAS
HNRNPG,HNRPG,MRXS11,RBMXP1,RBMXRT,RNMX,hnRNP-G
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 27316
MIM: 300199
HGNC: 9910
Ensembl: ENSG00000147274

Variants:

dbSNP: 27316
ClinVar: 27316
TCGA: ENSG00000147274
COSMIC: RBMX

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000147274ENST00000320676P38159
ENSG00000147274ENST00000419968H0Y6E7
ENSG00000147274ENST00000431446P38159
ENSG00000147274ENST00000464781H3BR27
ENSG00000147274ENST00000562646H3BT71
ENSG00000147274ENST00000563370H3BNC1
ENSG00000147274ENST00000565438H3BUY5
ENSG00000147274ENST00000568578H3BR27

Expression (GTEx)

0
50
100
150
200
250
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
SpliceosomeKEGGko03040
SpliceosomeKEGGhsa03040
Gene ExpressionREACTOMER-HSA-74160
Processing of Capped Intron-Containing Pre-mRNAREACTOMER-HSA-72203
mRNA SplicingREACTOMER-HSA-72172
mRNA Splicing - Major PathwayREACTOMER-HSA-72163

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
223440292012A genome-wide homologous recombination screen identifies the RNA-binding protein RBMX as a component of the DNA-damage response.162
283349032017N6-methyladenosine alters RNA structure to regulate binding of a low-complexity protein.91
228322232012RBMX: a regulator for maintenance and centromeric protection of sister chromatid cohesion.19
165527542006Positive correlation between the expression of X-chromosome RBM genes (RBMX, RBM3, RBM10) and the proapoptotic Bax gene in human breast cancer.18
314458862019Regulation of Co-transcriptional Pre-mRNA Splicing by m6A through the Low-Complexity Protein hnRNPG.16
185411472008hnRNP G elicits tumor-suppressive activity in part by upregulating the expression of Txnip.13
173870442007p53 promotes the fidelity of DNA end-joining activity by, in part, enhancing the expression of heterogeneous nuclear ribonucleoprotein G.12
258844342015HNRNP G and HTRA2-BETA1 regulate estrogen receptor alpha expression with potential impact on endometrial cancer.9
252567572015The RBMX gene as a candidate for the Shashi X-linked intellectual disability syndrome.8
184454772008An association between RBMX, a heterogeneous nuclear ribonucleoprotein, and ARTS-1 regulates extracellular TNFR1 release.7

Citation

Dessen P

RBMX (RNA binding motif protein X-linked)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/43822/rbmx