RBPMS (RNA binding protein, mRNA processing factor)

2010-01-01  

Identity

HGNC
LOCATION
8p12
LOCUSID
ALIAS
HERMES
FUSION GENES

Other Information

Locus ID:

NCBI: 11030
MIM: 601558
HGNC: 19097
Ensembl: ENSG00000157110

Variants:

dbSNP: 11030
ClinVar: 11030
TCGA: ENSG00000157110
COSMIC: RBPMS

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000157110ENST00000287771Q93062
ENSG00000157110ENST00000320203Q93062
ENSG00000157110ENST00000339877Q93062
ENSG00000157110ENST00000397323Q93062
ENSG00000157110ENST00000517860B4E3T4
ENSG00000157110ENST00000519359H0YBU9
ENSG00000157110ENST00000519647E5RFP4
ENSG00000157110ENST00000520161E5RFP4
ENSG00000157110ENST00000520191E5RJ31
ENSG00000157110ENST00000522694H0YC46
ENSG00000157110ENST00000523115E5RJD7

Expression (GTEx)

0
50
100
150
200
250
300

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
271669992016Targeting miR-21-3p inhibits proliferation and invasion of ovarian cancer cells.24
297437232018Dysregulation of EZH2/miR-138 axis contributes to drug resistance in multiple myeloma by downregulating RBPMS.18
280173752017Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.14
252813862015The RNA-binding protein RBPMS1 represses AP-1 signaling and regulates breast cancer cell proliferation and migration.13
272735142016The transcription factor ERG recruits CCR4-NOT to control mRNA decay and mitotic progression.11
280035152017Conserved binding of GCAC motifs by MEC-8, couch potato, and the RBPMS protein family.6
295421672018Inhibition of microRNA-21-3p suppresses proliferation as well as invasion and induces apoptosis by targeting RNA-binding protein with multiple splicing through Smad4/extra cellular signal-regulated protein kinase signalling pathway in human colorectal cancer HCT116 cells.5
275928362016Exploring the molecular basis of RNA recognition by the dimeric RNA-binding protein via molecular simulation methods.4
294236562018RNA-binding protein Rbpms is represented in human retinas by isoforms A and C and its transcriptional regulation involves Sp1-binding site.1

Citation

Dessen P

RBPMS (RNA binding protein, mRNA processing factor)

Atlas Genet Cytogenet Oncol Haematol. 2010-01-01

Online version: http://atlasgeneticsoncology.org/gene/51248/rbpms