Atlas of Genetics and Cytogenetics in Oncology and Haematology

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RDH10 (retinol dehydrogenase 10)

Identity

Alias (NCBI)SDR16C4
HGNC (Hugo) RDH10
HGNC Alias symbSDR16C4
HGNC Alias nameshort chain dehydrogenase/reductase family 16C, member 4
HGNC Previous nameretinol dehydrogenase 10 (all-trans)
LocusID (NCBI) 157506
Atlas_Id 49788
Location 8q21.11  [Link to chromosome band 8q21]
Location_base_pair Starts at 73294602 and ends at 73325281 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
JA040725 () / RDH10 (8q21.11)NEDD4 (15q21.3) / RDH10 (8q21.11)RDH10 (8q21.11) / NEDD4 (15q21.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)RDH10   19975
Cards
Entrez_Gene (NCBI)RDH10    retinol dehydrogenase 10
AliasesSDR16C4
GeneCards (Weizmann)RDH10
Ensembl hg19 (Hinxton)ENSG00000121039 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000121039 [Gene_View]  ENSG00000121039 [Sequence]  chr8:73294602-73325281 [Contig_View]  RDH10 [Vega]
ICGC DataPortalENSG00000121039
TCGA cBioPortalRDH10
AceView (NCBI)RDH10
Genatlas (Paris)RDH10
SOURCE (Princeton)RDH10
Genetics Home Reference (NIH)RDH10
Genomic and cartography
GoldenPath hg38 (UCSC)RDH10  -     chr8:73294602-73325281 +  8q21.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RDH10  -     8q21.11   [Description]    (hg19-Feb_2009)
GoldenPathRDH10 - 8q21.11 [CytoView hg19]  RDH10 - 8q21.11 [CytoView hg38]
ImmunoBaseENSG00000121039
genome Data Viewer NCBIRDH10 [Mapview hg19]  
OMIM607599   
Gene and transcription
Genbank (Entrez)AF456765 AY358270 BC067131 BM472905 BM804062
RefSeq transcript (Entrez)NM_172037
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RDH10
Alternative Splicing GalleryENSG00000121039
Gene ExpressionRDH10 [ NCBI-GEO ]   RDH10 [ EBI - ARRAY_EXPRESS ]   RDH10 [ SEEK ]   RDH10 [ MEM ]
Gene Expression Viewer (FireBrowse)RDH10 [ Firebrowse - Broad ]
GenevisibleExpression of RDH10 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)157506
GTEX Portal (Tissue expression)RDH10
Human Protein AtlasENSG00000121039-RDH10 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IZV5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8IZV5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8IZV5
Splice isoforms : SwissVarQ8IZV5
Catalytic activity : Enzyme1.1.1.300 [ Enzyme-Expasy ]   1.1.1.3001.1.1.300 [ IntEnz-EBI ]   1.1.1.300 [ BRENDA ]   1.1.1.300 [ KEGG ]   [ MEROPS ]
PhosPhoSitePlusQ8IZV5
Domaine pattern : Prosite (Expaxy)ADH_SHORT (PS00061)   
Domains : Interpro (EBI)NAD(P)-bd_dom_sf    RDH10    Sc_DH/Rdtase_CS    SDR_fam   
Domain families : Pfam (Sanger)adh_short (PF00106)   
Domain families : Pfam (NCBI)pfam00106   
Conserved Domain (NCBI)RDH10
Blocks (Seattle)RDH10
SuperfamilyQ8IZV5
Human Protein Atlas [tissue]ENSG00000121039-RDH10 [tissue]
Peptide AtlasQ8IZV5
HPRD07605
IPIIPI00218086   IPI00981424   IPI00982065   
Protein Interaction databases
DIP (DOE-UCLA)Q8IZV5
IntAct (EBI)Q8IZV5
BioGRIDRDH10
STRING (EMBL)RDH10
ZODIACRDH10
Ontologies - Pathways
QuickGOQ8IZV5
Ontology : AmiGOretinoid metabolic process  metanephros development  in utero embryonic development  retinoic acid biosynthetic process  retinol dehydrogenase activity  protein binding  nucleus  cytoplasm  endoplasmic reticulum membrane  lipid droplet  visual perception  gonad development  neural crest cell development  integral component of membrane  oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor  embryonic camera-type eye development  embryonic forelimb morphogenesis  retinol metabolic process  retinol metabolic process  retinal metabolic process  ear development  nose development  embryonic viscerocranium morphogenesis  NADP-retinol dehydrogenase activity  primary lung bud formation  bud elongation involved in lung branching  positive regulation of retinoic acid biosynthetic process  
Ontology : EGO-EBIretinoid metabolic process  metanephros development  in utero embryonic development  retinoic acid biosynthetic process  retinol dehydrogenase activity  protein binding  nucleus  cytoplasm  endoplasmic reticulum membrane  lipid droplet  visual perception  gonad development  neural crest cell development  integral component of membrane  oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor  embryonic camera-type eye development  embryonic forelimb morphogenesis  retinol metabolic process  retinol metabolic process  retinal metabolic process  ear development  nose development  embryonic viscerocranium morphogenesis  NADP-retinol dehydrogenase activity  primary lung bud formation  bud elongation involved in lung branching  positive regulation of retinoic acid biosynthetic process  
Pathways : KEGGRetinol metabolism   
NDEx NetworkRDH10
Atlas of Cancer Signalling NetworkRDH10
Wikipedia pathwaysRDH10
Orthology - Evolution
OrthoDB157506
GeneTree (enSembl)ENSG00000121039
Phylogenetic Trees/Animal Genes : TreeFamRDH10
HOGENOMQ8IZV5
Homologs : HomoloGeneRDH10
Homology/Alignments : Family Browser (UCSC)RDH10
Gene fusions - Rearrangements
Fusion : MitelmanNEDD4/RDH10 [15q21.3/8q21.11]  
Fusion : MitelmanRDH10/NEDD4 [8q21.11/15q21.3]  
Fusion Cancer (Beijing)JA040725 [RDH10]  -  8q21.11 [FUSC001195]
Fusion : QuiverRDH10
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRDH10 [hg38]
dbVarRDH10
ClinVarRDH10
MonarchRDH10
1000_GenomesRDH10 
Exome Variant ServerRDH10
GNOMAD BrowserENSG00000121039
Varsome BrowserRDH10
Genomic Variants (DGV)RDH10 [DGVbeta]
DECIPHERRDH10 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRDH10 
Mutations
ICGC Data PortalRDH10 
TCGA Data PortalRDH10 
Broad Tumor PortalRDH10
OASIS PortalRDH10 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRDH10  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DRDH10
Mutations and Diseases : HGMDRDH10
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RDH10
DgiDB (Drug Gene Interaction Database)RDH10
DoCM (Curated mutations)RDH10 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RDH10 (select a term)
intoGenRDH10
Cancer3DRDH10(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607599   
Orphanet
DisGeNETRDH10
MedgenRDH10
Genetic Testing Registry RDH10
NextProtQ8IZV5 [Medical]
GENETestsRDH10
Target ValidationRDH10
Huge Navigator RDH10 [HugePedia]
ClinGenRDH10
Clinical trials, drugs, therapy
MyCancerGenomeRDH10
Protein Interactions : CTD
Pharm GKB GenePA134989620
PharosQ8IZV5
Clinical trialRDH10
Miscellaneous
canSAR (ICR)RDH10 (select the gene name)
HarmonizomeRDH10
DataMed IndexRDH10
Probes
Litterature
PubMed28 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXRDH10
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 25 19:42:56 CET 2021
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