REG1A (regenerating family member 1 alpha)

2006-08-01  

Identity

HGNC
REG1A
LOCATION
2p12
LOCUSID
5967
ALIAS
ICRF,P19,PSP,PSPS,PSPS1,PTP,REG
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 5967
MIM: 167770
HGNC: 9951
Ensembl: ENSG00000115386

Variants:

dbSNP: 5967
ClinVar: 5967
TCGA: ENSG00000115386
COSMIC: REG1A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000115386ENST00000233735P05451

Expression (GTEx)

0
10000
20000
30000
40000
50000
60000
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
262402912015Identification of a Three-Biomarker Panel in Urine for Early Detection of Pancreatic Adenocarcinoma.39
200659462010Involvement of the IL-22/REG Ialpha axis in ulcerative colitis.32
157654002005REG Ialpha protein may function as a trophic and/or anti-apoptotic factor in the development of gastric cancer.31
180244792008REG Ialpha protein mediates an anti-apoptotic effect of STAT3 signaling in gastric cancer cells.28
215863352011The expression of REG 1A and REG 1B is increased during acute amebic colitis.22
235194542013REG gene expression in inflamed and healthy colon mucosa explored by in situ hybridisation.22
235313372013Sepsis biomarkers in unselected patients on admission to intensive or high-dependency care.18
240554472013Pancreatic β cell proliferation by intermittent hypoxia via up-regulation of Reg family genes and HGF gene.17
151664872004Expression of reg I alpha protein in human gastric cancers.15

Citation

Dessen P

REG1A (regenerating family member 1 alpha)

Atlas Genet Cytogenet Oncol Haematol. 2006-08-01

Online version: http://atlasgeneticsoncology.org/gene/53311/reg1a