RETN (resistin)

2007-02-01 Affiliation

Identity

HGNC

RETN

LOCATION

19p13.2

LOCUSID

56729

ALIAS

ADSF,FIZZ3,RETN1,RSTN,XCP1

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 56729
MIM: 605565
HGNC: 20389
Ensembl: ENSG00000104918

Variants:

dbSNP: 56729
ClinVar: 56729
TCGA: ENSG00000104918
COSMIC: RETN

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000104918	ENST00000221515	Q9HD89
ENSG00000104918	ENST00000381324	Q9HD89
ENSG00000104918	ENST00000629642	Q9HD89

Expression (GTEx)

100

150

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Immune System	REACTOME	R-HSA-168256
Innate Immune System	REACTOME	R-HSA-168249
Neutrophil degranulation	REACTOME	R-HSA-6798695

References

Pubmed ID	Year	Title	Citations
15843582	2005	Resistin, an adipokine with potent proinflammatory properties.	226
12504108	2003	Resistin is expressed in human macrophages and directly regulated by PPAR gamma activators.	193
16039994	2005	Human resistin stimulates the pro-inflammatory cytokines TNF-alpha and IL-12 in macrophages by NF-kappaB-dependent pathway.	121
16496121	2006	Macrophages in human visceral adipose tissue: increased accumulation in obesity and a source of resistin and visfatin.	119
12874180	2003	Resistin promotes endothelial cell activation: further evidence of adipokine-endothelial interaction.	113
14514348	2003	Plasma resistin, adiponectin and leptin levels in lean and obese subjects: correlations with insulin resistance.	106
14557464	2003	Circulating resistin levels are not associated with obesity or insulin resistance in humans and are not regulated by fasting or leptin administration: cross-sectional and interventional studies in normal, insulin-resistant, and diabetic subjects.	105
21497511	2011	Human resistin: found in translation from mouse to man.	90
14602788	2003	Serum resistin (FIZZ3) protein is increased in obese humans.	85
19913121	2009	Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.	85

Citation

Dessen P

RETN (resistin)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46161/retn