Identity
HGNC
LOCATION
11q23.2
LOCUSID
ALIAS
CGI-114,REX2,RFN,SFN
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 25996
MIM: 607149
HGNC: 17851
Ensembl: ENSG00000076043
Variants:
dbSNP: 25996
ClinVar: 25996
TCGA: ENSG00000076043
COSMIC: REXO2
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Ribosome biogenesis in eukaryotes | KEGG | ko03008 |
| Ribosome biogenesis in eukaryotes | KEGG | hsa03008 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34088969 | 2021 | RUNX1 and REXO2 are associated with the heterogeneity and prognosis of IDH wild type lower grade glioma. | 12 |
| 34088969 | 2021 | RUNX1 and REXO2 are associated with the heterogeneity and prognosis of IDH wild type lower grade glioma. | 12 |
| 32354376 | 2020 | Germline variant in REXO2 is a novel candidate gene in familial pheochromocytoma. | 5 |
| 32365187 | 2020 | Human REXO2 controls short mitochondrial RNAs generated by mtRNA processing and decay machinery to prevent accumulation of double-stranded RNA. | 13 |
| 32354376 | 2020 | Germline variant in REXO2 is a novel candidate gene in familial pheochromocytoma. | 5 |
| 32365187 | 2020 | Human REXO2 controls short mitochondrial RNAs generated by mtRNA processing and decay machinery to prevent accumulation of double-stranded RNA. | 13 |
| 30926754 | 2019 | Structural insights into nanoRNA degradation by human Rexo2. | 12 |
| 31588022 | 2019 | Dinucleotide Degradation by REXO2 Maintains Promoter Specificity in Mammalian Mitochondria. | 13 |
| 30926754 | 2019 | Structural insights into nanoRNA degradation by human Rexo2. | 12 |
| 31588022 | 2019 | Dinucleotide Degradation by REXO2 Maintains Promoter Specificity in Mammalian Mitochondria. | 13 |
| 26346170 | 2016 | 14-3-3σ confers cisplatin resistance in esophageal squamous cell carcinoma cells via regulating DNA repair molecules. | 9 |
| 26346170 | 2016 | 14-3-3σ confers cisplatin resistance in esophageal squamous cell carcinoma cells via regulating DNA repair molecules. | 9 |
| 26147002 | 2015 | 14-3-3 Binding and Sumoylation Concur to the Down-Modulation of β-catenin Antagonist chibby 1 in Chronic Myeloid Leukemia. | 5 |
| 26147002 | 2015 | 14-3-3 Binding and Sumoylation Concur to the Down-Modulation of β-catenin Antagonist chibby 1 in Chronic Myeloid Leukemia. | 5 |
| 23741365 | 2013 | REXO2 is an oligoribonuclease active in human mitochondria. | 38 |
Citation
Dessen P
REXO2 (RNA exonuclease 2)
Atlas Genet Cytogenet Oncol Haematol. 2004-04-01
Online version: http://atlasgeneticsoncology.org/gene/40321/rexo2
