Atlas of Genetics and Cytogenetics in Oncology and Haematology

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   
X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

RFX7 (regulatory factor X7)

Identity

Alias (NCBI)RFXDC2
HGNC (Hugo) RFX7
HGNC Alias symbFLJ12994
HGNC Previous nameRFXDC2
HGNC Previous nameregulatory factor X domain containing 2
 regulatory factor X, 7
LocusID (NCBI) 64864
Atlas_Id 72604
Location 15q21.3  [Link to chromosome band 15q21]
Location_base_pair Starts at 56090533 and ends at 56243285 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
DYX1C1 (15q21.3) / RFX7 (15q21.3)HN1 (17q25.1) / RFX7 (15q21.3)NEDD4 (15q21.3) / RFX7 (15q21.3)
RFX7 (15q21.3) / RFX7 (15q21.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  NEDD4/RFX7 (15q21)

External links

Nomenclature
HGNC (Hugo)RFX7   25777
Cards
Entrez_Gene (NCBI)RFX7    regulatory factor X7
AliasesRFXDC2
GeneCards (Weizmann)RFX7
Ensembl hg19 (Hinxton)ENSG00000181827 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000181827 [Gene_View]  ENSG00000181827 [Sequence]  chr15:56090533-56243285 [Contig_View]  RFX7 [Vega]
ICGC DataPortalENSG00000181827
TCGA cBioPortalRFX7
AceView (NCBI)RFX7
Genatlas (Paris)RFX7
SOURCE (Princeton)RFX7
Genetics Home Reference (NIH)RFX7
Genomic and cartography
GoldenPath hg38 (UCSC)RFX7  -     chr15:56090533-56243285 -  15q21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RFX7  -     15q21.3   [Description]    (hg19-Feb_2009)
GoldenPathRFX7 - 15q21.3 [CytoView hg19]  RFX7 - 15q21.3 [CytoView hg38]
ImmunoBaseENSG00000181827
genome Data Viewer NCBIRFX7 [Mapview hg19]  
OMIM612660   
Gene and transcription
Genbank (Entrez)AK023056 AK024757 AK126103 AK128045 AL832584
RefSeq transcript (Entrez)NM_001368073 NM_001368074 NM_001370554 NM_001370561 NM_022841
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RFX7
Alternative Splicing GalleryENSG00000181827
Gene ExpressionRFX7 [ NCBI-GEO ]   RFX7 [ EBI - ARRAY_EXPRESS ]   RFX7 [ SEEK ]   RFX7 [ MEM ]
Gene Expression Viewer (FireBrowse)RFX7 [ Firebrowse - Broad ]
GenevisibleExpression of RFX7 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)64864
GTEX Portal (Tissue expression)RFX7
Human Protein AtlasENSG00000181827-RFX7 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ2KHR2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ2KHR2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ2KHR2
Splice isoforms : SwissVarQ2KHR2
PhosPhoSitePlusQ2KHR2
Domaine pattern : Prosite (Expaxy)RFX_DBD (PS51526)   
Domains : Interpro (EBI)DNA-bd_RFX    RFX-like    WH-like_DNA-bd_sf    WH_DNA-bd_sf   
Domain families : Pfam (Sanger)RFX_DNA_binding (PF02257)   
Domain families : Pfam (NCBI)pfam02257   
Conserved Domain (NCBI)RFX7
Blocks (Seattle)RFX7
PDB (RSDB)4QQI    6MEW   
PDB Europe4QQI    6MEW   
PDB (PDBSum)4QQI    6MEW   
PDB (IMB)4QQI    6MEW   
Structural Biology KnowledgeBase4QQI    6MEW   
SCOP (Structural Classification of Proteins)4QQI    6MEW   
CATH (Classification of proteins structures)4QQI    6MEW   
SuperfamilyQ2KHR2
Human Protein Atlas [tissue]ENSG00000181827-RFX7 [tissue]
Peptide AtlasQ2KHR2
HPRD07807
IPIIPI00896539   IPI00943243   IPI00640136   
Protein Interaction databases
DIP (DOE-UCLA)Q2KHR2
IntAct (EBI)Q2KHR2
BioGRIDRFX7
STRING (EMBL)RFX7
ZODIACRFX7
Ontologies - Pathways
QuickGOQ2KHR2
Ontology : AmiGOnuclear chromatin  RNA polymerase II proximal promoter sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity  nucleus  regulation of transcription by RNA polymerase II  
Ontology : EGO-EBInuclear chromatin  RNA polymerase II proximal promoter sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity  nucleus  regulation of transcription by RNA polymerase II  
NDEx NetworkRFX7
Atlas of Cancer Signalling NetworkRFX7
Wikipedia pathwaysRFX7
Orthology - Evolution
OrthoDB64864
GeneTree (enSembl)ENSG00000181827
Phylogenetic Trees/Animal Genes : TreeFamRFX7
HOGENOMQ2KHR2
Homologs : HomoloGeneRFX7
Homology/Alignments : Family Browser (UCSC)RFX7
Gene fusions - Rearrangements
Fusion : QuiverRFX7
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRFX7 [hg38]
dbVarRFX7
ClinVarRFX7
MonarchRFX7
1000_GenomesRFX7 
Exome Variant ServerRFX7
GNOMAD BrowserENSG00000181827
Varsome BrowserRFX7
Genomic Variants (DGV)RFX7 [DGVbeta]
DECIPHERRFX7 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRFX7 
Mutations
ICGC Data PortalRFX7 
TCGA Data PortalRFX7 
Broad Tumor PortalRFX7
OASIS PortalRFX7 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRFX7  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DRFX7
Mutations and Diseases : HGMDRFX7
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RFX7
DgiDB (Drug Gene Interaction Database)RFX7
DoCM (Curated mutations)RFX7 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RFX7 (select a term)
intoGenRFX7
Cancer3DRFX7(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612660   
Orphanet
DisGeNETRFX7
MedgenRFX7
Genetic Testing Registry RFX7
NextProtQ2KHR2 [Medical]
GENETestsRFX7
Target ValidationRFX7
Huge Navigator RFX7 [HugePedia]
ClinGenRFX7
Clinical trials, drugs, therapy
MyCancerGenomeRFX7
Protein Interactions : CTD
Pharm GKB GenePA162401255
Clinical trialRFX7
Miscellaneous
canSAR (ICR)RFX7 (select the gene name)
HarmonizomeRFX7
DataMed IndexRFX7
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRFX7
EVEXRFX7
GoPubMedRFX7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Dec 5 17:24:35 CET 2020
Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.