RGCC (regulator of cell cycle)

2003-02-01  

Identity

HGNC
LOCATION
13q14.11
LOCUSID
ALIAS
C13orf15,RGC-32,RGC32,bA157L14.2
FUSION GENES

Other Information

Locus ID:

NCBI: 28984
MIM: 610077
HGNC: 20369
Ensembl: ENSG00000102760

Variants:

dbSNP: 28984
ClinVar: 28984
TCGA: ENSG00000102760
COSMIC: RGCC

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000102760ENST00000379359Q9H4X1

Expression (GTEx)

0
500
1000
1500

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
Generic Transcription PathwayREACTOMER-HSA-212436
Transcriptional Regulation by TP53REACTOMER-HSA-3700989
TP53 Regulates Transcription of Cell Cycle GenesREACTOMER-HSA-6791312
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertainREACTOMER-HSA-6804115

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
354620502022RGC-32' dual role in smooth muscle cells and atherogenesis.3
361723822022Role of RGC-32 in multiple sclerosis and neuroinflammation - few answers and many questions.1
354620502022RGC-32' dual role in smooth muscle cells and atherogenesis.3
361723822022Role of RGC-32 in multiple sclerosis and neuroinflammation - few answers and many questions.1
323255392020Oncogenic gene RGC-32 is a direct target of miR-26b and facilitates tongue squamous cell carcinoma aggressiveness through EMT and PI3K/AKT signalling.2
323255392020Oncogenic gene RGC-32 is a direct target of miR-26b and facilitates tongue squamous cell carcinoma aggressiveness through EMT and PI3K/AKT signalling.2
306005422019Decreased expression of response gene to complement 32 in psoriasis and its association with reduced M2 macrophage polarization.6
316017832019Response gene to complement 32 expression in macrophages augments paracrine stimulation-mediated colon cancer progression.8
306005422019Decreased expression of response gene to complement 32 in psoriasis and its association with reduced M2 macrophage polarization.6
316017832019Response gene to complement 32 expression in macrophages augments paracrine stimulation-mediated colon cancer progression.8
293855362018Pumilio directs deadenylation-associated translational repression of the cyclin-dependent kinase 1 activator RGC-32.8
293855362018Pumilio directs deadenylation-associated translational repression of the cyclin-dependent kinase 1 activator RGC-32.8
279384912017Regulator of Cell Cycle (RGCC) Expression During the Progression of Alzheimer's Disease.18
284701882017RGC32 induces epithelial-mesenchymal transition by activating the Smad/Sip1 signaling pathway in CRC.9
290358862017Response Gene to Complement-32 Promotes the Imbalance of Treg/Th17 in Patients with Dilated Cardiomyopathy.5

Citation

Dessen P

RGCC (regulator of cell cycle)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/42096/rgcc