RGS10 (regulator of G protein signaling 10)

2007-04-01  

Identity

HGNC
LOCATION
10q26.11
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 6001
MIM: 602856
HGNC: 9992
Ensembl: ENSG00000148908

Variants:

dbSNP: 6001
ClinVar: 6001
TCGA: ENSG00000148908
COSMIC: RGS10

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000148908ENST00000369101O43665
ENSG00000148908ENST00000369103O43665
ENSG00000148908ENST00000392865O43665

Expression (GTEx)

0
50
100
150
200

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR downstream signalingREACTOMER-HSA-388396
G alpha (i) signalling eventsREACTOMER-HSA-418594

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
383311182024Epigenetic insights into Familial Mediterranean Fever: Increased RGS10 expression and histone modifications accompanies inflammation in familial Mediterranean fever disease.0
383311182024Epigenetic insights into Familial Mediterranean Fever: Increased RGS10 expression and histone modifications accompanies inflammation in familial Mediterranean fever disease.0
358105652022RGS10 suppression by DNA methylation is associated with low survival rates in colorectal carcinoma.3
358105652022RGS10 suppression by DNA methylation is associated with low survival rates in colorectal carcinoma.3
333548112021A broad analysis in clinical and in vitro models on regulator of G-protein signalling 10 regulation that is associated with ovarian cancer progression and chemoresistance.1
343158062021Short stature and combined immunodeficiency associated with mutations in RGS10.2
344127042021Experimental colitis promotes sustained, sex-dependent, T-cell-associated neuroinflammation and parkinsonian neuropathology.25
333548112021A broad analysis in clinical and in vitro models on regulator of G-protein signalling 10 regulation that is associated with ovarian cancer progression and chemoresistance.1
343158062021Short stature and combined immunodeficiency associated with mutations in RGS10.2
344127042021Experimental colitis promotes sustained, sex-dependent, T-cell-associated neuroinflammation and parkinsonian neuropathology.25
328824072020Regulator of G protein signaling 10: Structure, expression and functions in cellular physiology and diseases.10
328824072020Regulator of G protein signaling 10: Structure, expression and functions in cellular physiology and diseases.10
300498162018RGS10 Regulates the Expression of Cyclooxygenase-2 and Tumor Necrosis Factor Alpha through a G Protein-Independent Mechanism.12
300498162018RGS10 Regulates the Expression of Cyclooxygenase-2 and Tumor Necrosis Factor Alpha through a G Protein-Independent Mechanism.12
262933482015Cellular deficiency in the RGS10 protein facilitates chemoresistant ovarian cancer.6

Citation

Dessen P

RGS10 (regulator of G protein signaling 10)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/47421/rgs10