RGS11 (regulator of G protein signaling 11)

2007-04-01  

Identity

HGNC
LOCATION
16p13.3
LOCUSID
ALIAS
RS11

Other Information

Locus ID:

NCBI: 8786
MIM: 603895
HGNC: 9993
Ensembl: ENSG00000076344

Variants:

dbSNP: 8786
ClinVar: 8786
TCGA: ENSG00000076344
COSMIC: RGS11

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000076344ENST00000168869H7C5Z0
ENSG00000076344ENST00000316163O94810
ENSG00000076344ENST00000359740O94810
ENSG00000076344ENST00000397770O94810
ENSG00000076344ENST00000397770Q4TT70

Expression (GTEx)

0
50
100
150
200
250
300
350
400
450

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Protein foldingREACTOMER-HSA-391251
Chaperonin-mediated protein foldingREACTOMER-HSA-390466
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR downstream signalingREACTOMER-HSA-388396
G alpha (i) signalling eventsREACTOMER-HSA-418594
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta foldingREACTOMER-HSA-6814122

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
204530002010A Large-scale genetic association study of esophageal adenocarcinoma risk.23
271055002016Overexpression of regulator of G protein signaling 11 promotes cell migration and associates with advanced stages and aggressiveness of lung adenocarcinoma.8
206278712010Genetic variations in regulator of G-protein signaling genes as susceptibility loci for second primary tumor/recurrence in head and neck squamous cell carcinoma.5
248286082014Differential expression of poliovirus receptor, regulator of G-protein signaling 11 and erythrocyte protein band 4.1-like 3 in human granulosa cells during follicular growth and maturation.2
194973062009RGS11 interacts preferentially with R7BP over Galpha(oa)--characterization of Gbeta5-free RGS11.1

Citation

Dessen P

RGS11 (regulator of G protein signaling 11)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/47277/rgs11