RILP (Rab interacting lysosomal protein)

2009-03-01  

Identity

HGNC
LOCATION
17p13.3
LOCUSID
ALIAS
PP10141

Other Information

Locus ID:

NCBI: 83547
MIM: 607848
HGNC: 30266
Ensembl: ENSG00000167705

Variants:

dbSNP: 83547
ClinVar: 83547
TCGA: ENSG00000167705
COSMIC: RILP

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000167705ENST00000301336Q96NA2
ENSG00000167705ENST00000574810I3L1U0

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Pathways

PathwaySourceExternal ID
PhagosomeKEGGko04145
PhagosomeKEGGhsa04145
Salmonella infectionKEGGko05132
Salmonella infectionKEGGhsa05132
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
MHC class II antigen presentationREACTOMER-HSA-2132295

References

Pubmed IDYearTitleCitations
195644042009Cholesterol sensor ORP1L contacts the ER protein VAP to control Rab7-RILP-p150 Glued and late endosome positioning.195
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
237297322013Late endosomal transport and tethering are coupled processes controlled by RILP and the cholesterol sensor ORP1L.64
159337192005Structural basis for recruitment of RILP by small GTPase Rab7.47
179596292007RILP is required for the proper morphology and function of late endosomes.41
189227952008Huntingtin regulates RE1-silencing transcription factor/neuron-restrictive silencer factor (REST/NRSF) nuclear trafficking indirectly through a complex with REST/NRSF-interacting LIM domain protein (RILP) and dynactin p150 Glued.27
164175802006Characterization of the REST/NRSF-interacting LIM domain protein (RILP): localization and interaction with REST/NRSF.20
168571642006RILP interacts with the VPS22 component of the ESCRT-II complex.19
247628122014RILP regulates vacuolar ATPase through interaction with the V1G1 subunit.18
254455622014RILP interacts with HOPS complex via VPS41 subunit to regulate endocytic trafficking.18

Citation

Dessen P

RILP (Rab interacting lysosomal protein)

Atlas Genet Cytogenet Oncol Haematol. 2009-03-01

Online version: http://atlasgeneticsoncology.org/gene/50721/rilp