Identity
HGNC
LOCATION
6p24.3
LOCUSID
ALIAS
AD034,RIO1,RRP10,bA288G3.1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 83732
MIM: 617753
HGNC: 18656
Ensembl: ENSG00000124784
Variants:
dbSNP: 83732
ClinVar: 83732
TCGA: ENSG00000124784
COSMIC: RIOK1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000124784 | ENST00000379834 | Q9BRS2 |
| ENSG00000124784 | ENST00000475351 | E9PFQ8 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37301535 | 2023 | The Oncogenic Protein Kinase/ATPase RIOK1 Is Up-Regulated via the c-myc/E2F Transcription Factor Axis in Prostate Cancer. | 1 |
| 37301535 | 2023 | The Oncogenic Protein Kinase/ATPase RIOK1 Is Up-Regulated via the c-myc/E2F Transcription Factor Axis in Prostate Cancer. | 1 |
| 35589951 | 2022 | RIOK1 mediates p53 degradation and radioresistance in colorectal cancer through phosphorylation of G3BP2. | 8 |
| 35589951 | 2022 | RIOK1 mediates p53 degradation and radioresistance in colorectal cancer through phosphorylation of G3BP2. | 8 |
| 33908345 | 2021 | The final step of 40S ribosomal subunit maturation is controlled by a dual key lock. | 17 |
| 33908345 | 2021 | The final step of 40S ribosomal subunit maturation is controlled by a dual key lock. | 17 |
| 32599985 | 2020 | Elevated Expression of RIOK1 Is Correlated with Breast Cancer Hormone Receptor Status and Promotes Cancer Progression. | 6 |
| 32599985 | 2020 | Elevated Expression of RIOK1 Is Correlated with Breast Cancer Hormone Receptor Status and Promotes Cancer Progression. | 6 |
| 29384474 | 2018 | Targeting posttranslational modifications of RIOK1 inhibits the progression of colorectal and gastric cancers. | 30 |
| 29384474 | 2018 | Targeting posttranslational modifications of RIOK1 inhibits the progression of colorectal and gastric cancers. | 30 |
| 27909846 | 2017 | Benzimidazole inhibitors of protein kinase CK2 potently inhibit the activity of atypical protein kinase Rio1. | 6 |
| 28499923 | 2017 | The Atypical Kinase RIOK1 Promotes Tumor Growth and Invasive Behavior. | 25 |
| 27909846 | 2017 | Benzimidazole inhibitors of protein kinase CK2 potently inhibit the activity of atypical protein kinase Rio1. | 6 |
| 28499923 | 2017 | The Atypical Kinase RIOK1 Promotes Tumor Growth and Invasive Behavior. | 25 |
| 27068473 | 2016 | MTAP Deletions in Cancer Create Vulnerability to Targeting of the MAT2A/PRMT5/RIOK1 Axis. | 165 |
Citation
Dessen P
RIOK1 (RIO kinase 1)
Atlas Genet Cytogenet Oncol Haematol. 2006-10-01
Online version: http://atlasgeneticsoncology.org/gene/43470/riok1
