RIOX1 (ribosomal oxygenase 1)

2016-12-01  

Identity

HGNC
RIOX1
LOCATION
14q24.3
LOCUSID
79697
ALIAS
C14orf169,JMJD9,MAPJD,NO66,ROX,URLC2,hsNO66

Other Information

Locus ID:

NCBI: 79697
MIM: 611919
HGNC: 20968
Ensembl: ENSG00000170468

Variants:

dbSNP: 79697
ClinVar: 79697
TCGA: ENSG00000170468
COSMIC: RIOX1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000170468ENST00000304061Q9H6W3

Expression (GTEx)

0
5
10
15
20
25
30
35
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
199271242010Regulation of the osteoblast-specific transcription factor Osterix by NO66, a Jumonji family histone demethylase.65
147427132004NO66, a highly conserved dual location protein in the nucleolus and in a special type of synchronously replicating chromatin.27
264889392015Expression of histone methyltransferases as novel biomarkers for renal cell tumor diagnosis and prognostication.15
236205902013Structural insights into histone demethylase NO66 in interaction with osteoblast-specific transcription factor osterix and gene repression.7
274735872017Clinical Significance of Histone Demethylase NO66 in Invasive Colorectal Cancer.4
227508592012Purification, crystallization and preliminary crystallographic analysis of histone lysine demethylase NO66 from Homo sapiens.2
263273852015Structure of the JmjC domain-containing protein NO66 complexed with ribosomal protein Rpl8.1
308585462019Oncogenic and osteolytic functions of histone demethylase NO66 in castration-resistant prostate cancer.0
317048262019The Histone Demethylase NO66 Induces Glioma Cell Proliferation.0

Citation

Dessen P

RIOX1 (ribosomal oxygenase 1)

Atlas Genet Cytogenet Oncol Haematol. 2016-12-01

Online version: http://atlasgeneticsoncology.org/gene/56658/riox1