Identity
HGNC
LOCATION
Xq13.2
LOCUSID
ALIAS
MRX61,NY-REN-43,RNF12,TOKAS
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 51132
MIM: 300379
HGNC: 13429
Ensembl: ENSG00000131263
Variants:
dbSNP: 51132
ClinVar: 51132
TCGA: ENSG00000131263
COSMIC: RLIM
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000131263 | ENST00000332687 | Q9NVW2 |
| ENSG00000131263 | ENST00000349225 | Q9NVW2 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38747697 | 2024 | How does the Xist activator Rlim/Rnf12 regulate Xist expression? | 0 |
| 38747697 | 2024 | How does the Xist activator Rlim/Rnf12 regulate Xist expression? | 0 |
| 37132043 | 2023 | Ring finger protein 12 activates AKT signalling to promote the progression of liver cancer by interacting with EGFR. | 1 |
| 37132043 | 2023 | Ring finger protein 12 activates AKT signalling to promote the progression of liver cancer by interacting with EGFR. | 1 |
| 35013159 | 2022 | RNF12 is regulated by AKT phosphorylation and promotes TGF-β driven breast cancer metastasis. | 6 |
| 35040952 | 2022 | Sequential stabilization of RNF220 by RLIM and ZC4H2 during cerebellum development and Shh-group medulloblastoma progression. | 4 |
| 35857630 | 2022 | An RNF12-USP26 amplification loop drives germ cell specification and is disrupted by disease-associated mutations. | 3 |
| 35013159 | 2022 | RNF12 is regulated by AKT phosphorylation and promotes TGF-β driven breast cancer metastasis. | 6 |
| 35040952 | 2022 | Sequential stabilization of RNF220 by RLIM and ZC4H2 during cerebellum development and Shh-group medulloblastoma progression. | 4 |
| 35857630 | 2022 | An RNF12-USP26 amplification loop drives germ cell specification and is disrupted by disease-associated mutations. | 3 |
| 33953269 | 2021 | A novel RLIM/RNF12 variant disrupts protein stability and function to cause severe Tonne-Kalscheuer syndrome. | 5 |
| 33953269 | 2021 | A novel RLIM/RNF12 variant disrupts protein stability and function to cause severe Tonne-Kalscheuer syndrome. | 5 |
| 31801865 | 2020 | Kaposi's Sarcoma-Associated Herpesvirus LANA Modulates the Stability of the E3 Ubiquitin Ligase RLIM. | 5 |
| 32416094 | 2020 | The RING Domain of RING Finger 12 Efficiently Builds Degradative Ubiquitin Chains. | 8 |
| 33159883 | 2020 | RLIM Is a Candidate Dosage-Sensitive Gene for Individuals with Varying Duplications of Xq13, Intellectual Disability, and Distinct Facial Features. | 4 |
Citation
Dessen P
RLIM (ring finger protein, LIM domain interacting)
Atlas Genet Cytogenet Oncol Haematol. 2003-06-01
Online version: http://atlasgeneticsoncology.org/gene/42127/rlim
