RMDN3 (regulator of microtubule dynamics 3)

2003-12-01  

Identity

HGNC
LOCATION
15q15.1
LOCUSID
ALIAS
FAM82A2,FAM82C,RMD-3,RMD3,ptpip51
FUSION GENES

Other Information

Locus ID:

NCBI: 55177
MIM: 611873
HGNC: 25550
Ensembl: ENSG00000137824

Variants:

dbSNP: 55177
ClinVar: 55177
TCGA: ENSG00000137824
COSMIC: RMDN3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000137824ENST00000260385Q96TC7
ENSG00000137824ENST00000260385A0A024R9P6
ENSG00000137824ENST00000338376Q96TC7
ENSG00000137824ENST00000338376A0A024R9P6
ENSG00000137824ENST00000558232H0YMB1
ENSG00000137824ENST00000558777H0YLV7
ENSG00000137824ENST00000560460H0YNE5
ENSG00000137824ENST00000560905H0YLG5

Expression (GTEx)

0
10
20
30
40
50
60

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
281328112017The ER-Mitochondria Tethering Complex VAPB-PTPIP51 Regulates Autophagy.68
168209672006Protein tyrosine phosphatase interacting protein 51 (PTPIP51) is a novel mitochondria protein with an N-terminal mitochondrial targeting sequence and induces apoptosis.17
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.17
219720922011PTPIP51, a positive modulator of the MAPK/Erk pathway, is upregulated in glioblastoma and interacts with 14-3-3β and PTP1B in situ.9
156090432005The novel protein PTPIP51 exhibits tissue- and cell-specific expression.7
225443072012PTPIP51 in protein interactions: regulation and in situ interacting partners.7
197732792009Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity.6
206277802010PTPIP51-a myeloid lineage specific protein interacts with PTP1B in neutrophil granulocytes.6
215139782011PTPIP51 is phosphorylated by Lyn and c-Src kinases lacking dephosphorylation by PTP1B in acute myeloid leukemia.6
245017732014The known interactome of PTPIP51 in HaCaT cells—inhibition of kinases and receptors.6

Citation

Dessen P

RMDN3 (regulator of microtubule dynamics 3)

Atlas Genet Cytogenet Oncol Haematol. 2003-12-01

Online version: http://atlasgeneticsoncology.org/gene/40586/rmdn3