RNASE1 (ribonuclease A family member 1, pancreatic)

2007-02-01  

Identity

HGNC
LOCATION
14q11.2
LOCUSID
ALIAS
RAC1,RIB1,RNS1
FUSION GENES

Other Information

Locus ID:

NCBI: 6035
MIM: 180440
HGNC: 10044
Ensembl: ENSG00000129538

Variants:

dbSNP: 6035
ClinVar: 6035
TCGA: ENSG00000129538
COSMIC: RNASE1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000129538ENST00000340900P07998
ENSG00000129538ENST00000340900W0UV93
ENSG00000129538ENST00000397967P07998
ENSG00000129538ENST00000397967W0UV93
ENSG00000129538ENST00000397970P07998
ENSG00000129538ENST00000397970W0UV93
ENSG00000129538ENST00000412779P07998
ENSG00000129538ENST00000412779W0UV93
ENSG00000129538ENST00000555698G3V357

Expression (GTEx)

0
500
1000
1500

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
339862892021Human ribonuclease 1 serves as a secretory ligand of ephrin A4 receptor and induces breast tumor initiation.12
339862892021Human ribonuclease 1 serves as a secretory ligand of ephrin A4 receptor and induces breast tumor initiation.12
326098222020Processing by RNase 1 forms tRNA halves and distinct Y RNA fragments in the extracellular environment.27
326098222020Processing by RNase 1 forms tRNA halves and distinct Y RNA fragments in the extracellular environment.27
306335042019Consequences of the Endogenous N-Glycosylation of Human Ribonuclease 1.11
310393282019Inflammation-mediated deacetylation of the ribonuclease 1 promoter via histone deacetylase 2 in endothelial cells.15
306335042019Consequences of the Endogenous N-Glycosylation of Human Ribonuclease 1.11
310393282019Inflammation-mediated deacetylation of the ribonuclease 1 promoter via histone deacetylase 2 in endothelial cells.15
278065712016Knockout of the Ribonuclease Inhibitor Gene Leaves Human Cells Vulnerable to Secretory Ribonucleases.17
278065712016Knockout of the Ribonuclease Inhibitor Gene Leaves Human Cells Vulnerable to Secretory Ribonucleases.17
253361202014Increased N-glycosylation of Asn⁸⁸ in serum pancreatic ribonuclease 1 is a novel diagnostic marker for pancreatic cancer.9
253361202014Increased N-glycosylation of Asn⁸⁸ in serum pancreatic ribonuclease 1 is a novel diagnostic marker for pancreatic cancer.9
241003292013Three-dimensional domain swapping and supramolecular protein assembly: insights from the X-ray structure of a dimeric swapped variant of human pancreatic RNase.7
241003292013Three-dimensional domain swapping and supramolecular protein assembly: insights from the X-ray structure of a dimeric swapped variant of human pancreatic RNase.7
231352722012Conservation of flexible residue clusters among structural and functional enzyme homologues.23

Citation

Dessen P

RNASE1 (ribonuclease A family member 1, pancreatic)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46115/rnase1