Identity
HGNC
LOCATION
14q11.2
LOCUSID
ALIAS
EDN,RAF3,RNS2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6036
MIM: 131410
HGNC: 10045
Ensembl: ENSG00000169385
Variants:
dbSNP: 6036
ClinVar: 6036
TCGA: ENSG00000169385
COSMIC: RNASE2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000169385 | ENST00000304625 | P10153 |
| ENSG00000169385 | ENST00000304625 | W0UV60 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Immune System | REACTOME | R-HSA-168256 |
| Innate Immune System | REACTOME | R-HSA-168249 |
| Neutrophil degranulation | REACTOME | R-HSA-6798695 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38374551 | 2024 | Addressing diagnostic dilemmas in eosinophilic esophagitis using esophageal epithelial eosinophil-derived neurotoxin. | 0 |
| 38374551 | 2024 | Addressing diagnostic dilemmas in eosinophilic esophagitis using esophageal epithelial eosinophil-derived neurotoxin. | 0 |
| 37105176 | 2023 | RNase2 is a possible trigger of acute-on-chronic inflammation leading to mRNA vaccine-associated cardiac complication. | 2 |
| 37174726 | 2023 | The Role of Eosinophil-Derived Neurotoxin and Vascular Endothelial Growth Factor in the Pathogenesis of Eosinophilic Asthma. | 2 |
| 37795650 | 2023 | Eosinophil-derived neurotoxin levels in early childhood and association with preschool asthma - A prospective observational study. | 0 |
| 37105176 | 2023 | RNase2 is a possible trigger of acute-on-chronic inflammation leading to mRNA vaccine-associated cardiac complication. | 2 |
| 37174726 | 2023 | The Role of Eosinophil-Derived Neurotoxin and Vascular Endothelial Growth Factor in the Pathogenesis of Eosinophilic Asthma. | 2 |
| 37795650 | 2023 | Eosinophil-derived neurotoxin levels in early childhood and association with preschool asthma - A prospective observational study. | 0 |
| 34615736 | 2022 | Blood eosinophil cationic protein and eosinophil-derived neurotoxin are associated with different asthma expression and evolution in adults. | 8 |
| 35265065 | 2022 | RNASE2 Mediates Age-Associated B Cell Expansion Through Monocyte Derived IL-10 in Patients With Systemic Lupus Erythematosus. | 10 |
| 34615736 | 2022 | Blood eosinophil cationic protein and eosinophil-derived neurotoxin are associated with different asthma expression and evolution in adults. | 8 |
| 35265065 | 2022 | RNASE2 Mediates Age-Associated B Cell Expansion Through Monocyte Derived IL-10 in Patients With Systemic Lupus Erythematosus. | 10 |
| 32571644 | 2021 | Combined assessment of serum eosinophil-derived neurotoxin and YKL-40 may identify Asthma-COPD overlap. | 5 |
| 32571644 | 2021 | Combined assessment of serum eosinophil-derived neurotoxin and YKL-40 may identify Asthma-COPD overlap. | 5 |
| 32294405 | 2020 | Immune Sensing of Synthetic, Bacterial, and Protozoan RNA by Toll-like Receptor 8 Requires Coordinated Processing by RNase T2 and RNase 2. | 57 |
Citation
Dessen P
RNASE2 (ribonuclease A family member 2)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46157/rnase2
