RNASE4 (ribonuclease A family member 4)

2014-11-01  

Identity

HGNC
RNASE4
LOCATION
14q11.2
LOCUSID
6038
ALIAS
RAB1,RNS4

Other Information

Locus ID:

NCBI: 6038
MIM: 601030
HGNC: 10047
Ensembl: ENSG00000258818

Variants:

dbSNP: 6038
ClinVar: 6038
TCGA: ENSG00000258818
COSMIC: RNASE4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000258818ENST00000397995P34096
ENSG00000258818ENST00000397995Q53XB4
ENSG00000258818ENST00000555597P34096
ENSG00000258818ENST00000555597Q53XB4
ENSG00000258818ENST00000555835P34096
ENSG00000258818ENST00000555835Q53XB4

Expression (GTEx)

0
50
100
150
200
250
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
205322022010Use of genome-wide expression data to mine the "Gray Zone" of GWA studies leads to novel candidate obesity genes.34
231436602013Ribonuclease 4 protects neuron degeneration by promoting angiogenesis, neurogenesis, and neuronal survival under stress.20
246597822014Transcription of angiogenin and ribonuclease 4 is regulated by RNA polymerase III elements and a CCCTC binding factor (CTCF)-dependent intragenic chromatin loop.13
293284422018Identification of differentially expressed genes and regulatory relationships in Huntington's disease by bioinformatics analysis.2
305440072019A molecular dynamics based investigation reveals the role of rare Ribonuclease 4 variants in amyotrophic lateral sclerosis susceptibility.2

Citation

Dessen P

RNASE4 (ribonuclease A family member 4)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/72668/rnase4