RNASE8 (ribonuclease A family member 8)

2014-11-01  

Identity

HGNC
RNASE8
LOCATION
14q11.2
LOCUSID
122665
ALIAS
RAE2

Other Information

Locus ID:

NCBI: 122665
MIM: 612485
HGNC: 19277
Ensembl: ENSG00000173431

Variants:

dbSNP: 122665
ClinVar: 122665
TCGA: ENSG00000173431
COSMIC: RNASE8

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000173431ENST00000308227Q8TDE3

Expression (GTEx)

0
1
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Antimicrobial peptidesREACTOMER-HSA-6803157

References

Pubmed IDYearTitleCitations
169401292006Identification of RNase 8 as a novel human antimicrobial protein.16
171166442007Disulfide-bond reshuffling in the evolution of an ape placental ribonuclease.7
222727362012Genetic diversity of human RNase 8.6

Citation

Dessen P

RNASE8 (ribonuclease A family member 8)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/72671/rnase8