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RNF115 (ring finger protein 115)

Identity

Alias_namesZNF364
zinc finger protein 364
Alias_symbol (synonym)CL469780
Other aliasBCA2
HGNC (Hugo) RNF115
LocusID (NCBI) 27246
Atlas_Id 53866
Location 1q21.1  [Link to chromosome band 1q21]
Location_base_pair Starts at 145746082 and ends at 145824123 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
BAZ1A (14q13.1) / RNF115 (1q21.1)DEFA1 (8p23.1) / RNF115 (1q21.1)RNF115 (1q21.1) / ARNTL2 (12p11.23)
RNF115 (1q21.1) / TRNAU1AP (1p35.3)TUFT1 (1q21.3) / RNF115 (1q21.1)BAZ1A 14q13.1 / RNF115 1q21.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(1;14)(q21;q13) BAZ1A/RNF115


External links

Nomenclature
HGNC (Hugo)RNF115   18154
Cards
Entrez_Gene (NCBI)RNF115  27246  ring finger protein 115
AliasesBCA2; ZNF364
GeneCards (Weizmann)RNF115
Ensembl hg19 (Hinxton)ENSG00000265491 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000265491 [Gene_View]  ENSG00000265491 [Sequence]  chr1:145746082-145824123 [Contig_View]  RNF115 [Vega]
ICGC DataPortalENSG00000265491
TCGA cBioPortalRNF115
AceView (NCBI)RNF115
Genatlas (Paris)RNF115
WikiGenes27246
SOURCE (Princeton)RNF115
Genetics Home Reference (NIH)RNF115
Genomic and cartography
GoldenPath hg38 (UCSC)RNF115  -     chr1:145746082-145824123 -  1q21.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RNF115  -     1q21.1   [Description]    (hg19-Feb_2009)
GoldenPathRNF115 - 1q21.1 [CytoView hg19]  RNF115 - 1q21.1 [CytoView hg38]
ImmunoBaseENSG00000265491
Mapping of homologs : NCBIRNF115 [Mapview hg19]  RNF115 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AF419857 AF542552 AK290749 AL079312 AL079314
RefSeq transcript (Entrez)NM_014455
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RNF115
Cluster EST : UnigeneHs.523550 [ NCBI ]
CGAP (NCI)Hs.523550
Alternative Splicing GalleryENSG00000265491
Gene ExpressionRNF115 [ NCBI-GEO ]   RNF115 [ EBI - ARRAY_EXPRESS ]   RNF115 [ SEEK ]   RNF115 [ MEM ]
Gene Expression Viewer (FireBrowse)RNF115 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)27246
GTEX Portal (Tissue expression)RNF115
Human Protein AtlasENSG00000265491-RNF115 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y4L5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y4L5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y4L5
Splice isoforms : SwissVarQ9Y4L5
PhosPhoSitePlusQ9Y4L5
Domaine pattern : Prosite (Expaxy)ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)Znf_RING    Znf_RING/FYVE/PHD   
Domain families : Pfam (Sanger)zf-RING_2 (PF13639)   
Domain families : Pfam (NCBI)pfam13639   
Domain families : Smart (EMBL)RING (SM00184)  
Conserved Domain (NCBI)RNF115
DMDM Disease mutations27246
Blocks (Seattle)RNF115
SuperfamilyQ9Y4L5
Human Protein Atlas [tissue]ENSG00000265491-RNF115 [tissue]
Peptide AtlasQ9Y4L5
HPRD18328
IPIIPI00337608   IPI01013887   IPI01012316   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y4L5
IntAct (EBI)Q9Y4L5
FunCoupENSG00000265491
BioGRIDRNF115
STRING (EMBL)RNF115
ZODIACRNF115
Ontologies - Pathways
QuickGOQ9Y4L5
Ontology : AmiGOprotein polyubiquitination  ubiquitin-protein transferase activity  protein binding  cytoplasm  cytosol  cytosol  protein ubiquitination  negative regulation of epidermal growth factor receptor signaling pathway  ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway  metal ion binding  protein autoubiquitination  ubiquitin protein ligase activity  ubiquitin protein ligase activity  protein K63-linked ubiquitination  protein K48-linked ubiquitination  
Ontology : EGO-EBIprotein polyubiquitination  ubiquitin-protein transferase activity  protein binding  cytoplasm  cytosol  cytosol  protein ubiquitination  negative regulation of epidermal growth factor receptor signaling pathway  ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway  metal ion binding  protein autoubiquitination  ubiquitin protein ligase activity  ubiquitin protein ligase activity  protein K63-linked ubiquitination  protein K48-linked ubiquitination  
NDEx NetworkRNF115
Atlas of Cancer Signalling NetworkRNF115
Wikipedia pathwaysRNF115
Orthology - Evolution
OrthoDB27246
GeneTree (enSembl)ENSG00000265491
Phylogenetic Trees/Animal Genes : TreeFamRNF115
HOGENOMQ9Y4L5
Homologs : HomoloGeneRNF115
Homology/Alignments : Family Browser (UCSC)RNF115
Gene fusions - Rearrangements
Fusion : MitelmanBAZ1A/RNF115 [14q13.1/1q21.1]  [t(1;14)(q21;q13)]  
Fusion PortalBAZ1A 14q13.1 RNF115 1q21.1 LUSC
Fusion : QuiverRNF115
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRNF115 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RNF115
dbVarRNF115
ClinVarRNF115
1000_GenomesRNF115 
Exome Variant ServerRNF115
ExAC (Exome Aggregation Consortium)ENSG00000265491
GNOMAD BrowserENSG00000265491
Varsome BrowserRNF115
Genetic variants : HAPMAP27246
Genomic Variants (DGV)RNF115 [DGVbeta]
DECIPHERRNF115 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRNF115 
Mutations
ICGC Data PortalRNF115 
TCGA Data PortalRNF115 
Broad Tumor PortalRNF115
OASIS PortalRNF115 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRNF115  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DRNF115
Mutations and Diseases : HGMDRNF115
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RNF115
DgiDB (Drug Gene Interaction Database)RNF115
DoCM (Curated mutations)RNF115 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RNF115 (select a term)
intoGenRNF115
Cancer3DRNF115(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETRNF115
MedgenRNF115
Genetic Testing Registry RNF115
NextProtQ9Y4L5 [Medical]
TSGene27246
GENETestsRNF115
Target ValidationRNF115
Huge Navigator RNF115 [HugePedia]
snp3D : Map Gene to Disease27246
BioCentury BCIQRNF115
ClinGenRNF115
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD27246
Chemical/Pharm GKB GenePA162401519
Clinical trialRNF115
Miscellaneous
canSAR (ICR)RNF115 (select the gene name)
DataMed IndexRNF115
Probes
Litterature
PubMed38 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRNF115
EVEXRNF115
GoPubMedRNF115
iHOPRNF115
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Nov 13 18:05:09 CET 2019

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