Identity
HGNC
LOCATION
3p21.31
LOCUSID
ALIAS
FP1477,KPC1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 63891
MIM: 614472
HGNC: 21148
Ensembl: ENSG00000164068
Variants:
dbSNP: 63891
ClinVar: 63891
TCGA: ENSG00000164068
COSMIC: RNF123
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36880841 | 2023 | The Tumor Suppressor Functions of Ubiquitin Ligase KPC1: From Cell-Cycle Control to NF-κB Regulator. | 3 |
| 36880841 | 2023 | The Tumor Suppressor Functions of Ubiquitin Ligase KPC1: From Cell-Cycle Control to NF-κB Regulator. | 3 |
| 33926923 | 2021 | Genome-wide association study identifies RNF123 locus as associated with chronic widespread musculoskeletal pain. | 20 |
| 34873064 | 2021 | A short binding site in the KPC1 ubiquitin ligase mediates processing of NF-κB1 p105 to p50: A potential for a tumor-suppressive PROTAC. | 1 |
| 33926923 | 2021 | Genome-wide association study identifies RNF123 locus as associated with chronic widespread musculoskeletal pain. | 20 |
| 34873064 | 2021 | A short binding site in the KPC1 ubiquitin ligase mediates processing of NF-κB1 p105 to p50: A potential for a tumor-suppressive PROTAC. | 1 |
| 33168738 | 2020 | Excess of the NF-ĸB p50 subunit generated by the ubiquitin ligase KPC1 suppresses tumors via PD-L1- and chemokines-mediated mechanisms. | 11 |
| 33168738 | 2020 | Excess of the NF-ĸB p50 subunit generated by the ubiquitin ligase KPC1 suppresses tumors via PD-L1- and chemokines-mediated mechanisms. | 11 |
| 29676528 | 2018 | E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins. | 20 |
| 29676528 | 2018 | E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins. | 20 |
| 28389511 | 2017 | Epigenetic Regulation of KPC1 Ubiquitin Ligase Affects the NF-κB Pathway in Melanoma. | 21 |
| 28601655 | 2017 | Regulation of p27 by ubiquitin ligases and its pathological significance in human lung carcinomas. | 6 |
| 28389511 | 2017 | Epigenetic Regulation of KPC1 Ubiquitin Ligase Affects the NF-κB Pathway in Melanoma. | 21 |
| 28601655 | 2017 | Regulation of p27 by ubiquitin ligases and its pathological significance in human lung carcinomas. | 6 |
| 27312109 | 2016 | RNF123 has an E3 ligase-independent function in RIG-I-like receptor-mediated antiviral signaling. | 11 |
Citation
Dessen P
RNF123 (ring finger protein 123)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/47473/rnf123
