Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 55658
MIM: 615177
HGNC: 21151
Ensembl: ENSG00000070423
Variants:
dbSNP: 55658
ClinVar: 55658
TCGA: ENSG00000070423
COSMIC: RNF126
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000070423 | ENST00000292363 | Q9BV68 |
| ENSG00000070423 | ENST00000292363 | A0A024R206 |
| ENSG00000070423 | ENST00000589762 | K7EIY6 |
| ENSG00000070423 | ENST00000605891 | U3KQF4 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36563124 | 2023 | RNF126-Mediated MRE11 Ubiquitination Activates the DNA Damage Response and Confers Resistance of Triple-Negative Breast Cancer to Radiotherapy. | 7 |
| 36563124 | 2023 | RNF126-Mediated MRE11 Ubiquitination Activates the DNA Damage Response and Confers Resistance of Triple-Negative Breast Cancer to Radiotherapy. | 7 |
| 36068398 | 2022 | RNF126 contributes to stem cell-like properties and metastasis in hepatocellular carcinoma through ubiquitination and degradation of LKB1. | 1 |
| 36539893 | 2022 | Ring finger protein 126 promotes breast cancer metastasis and serves as a potential target to improve the therapeutic sensitivity of ATR inhibitors. | 3 |
| 36068398 | 2022 | RNF126 contributes to stem cell-like properties and metastasis in hepatocellular carcinoma through ubiquitination and degradation of LKB1. | 1 |
| 36539893 | 2022 | Ring finger protein 126 promotes breast cancer metastasis and serves as a potential target to improve the therapeutic sensitivity of ATR inhibitors. | 3 |
| 33664240 | 2021 | E3 ubiquitin ligase RNF126 affects bladder cancer progression through regulation of PTEN stability. | 19 |
| 34388456 | 2021 | CHFR-mediated degradation of RNF126 confers sensitivity to PARP inhibitors in triple-negative breast cancer cells. | 4 |
| 34533052 | 2021 | Overexpression of RNF126 is associated with poor prognosis and contributes to the progression of lung adenocarcinoma. | 1 |
| 33664240 | 2021 | E3 ubiquitin ligase RNF126 affects bladder cancer progression through regulation of PTEN stability. | 19 |
| 34388456 | 2021 | CHFR-mediated degradation of RNF126 confers sensitivity to PARP inhibitors in triple-negative breast cancer cells. | 4 |
| 34533052 | 2021 | Overexpression of RNF126 is associated with poor prognosis and contributes to the progression of lung adenocarcinoma. | 1 |
| 32132033 | 2020 | RNF126 as a Marker of Prognosis and Proliferation of Gastric Cancer. | 9 |
| 32147403 | 2020 | Roles of RNF126 and BCA2 E3 ubiquitin ligases in DNA damage repair signaling and targeted cancer therapy. | 9 |
| 32254065 | 2020 | High Expression of RING Finger Protein 126 Predicts Unfavorable Prognosis of Epithelial Ovarian Cancer. | 4 |
Citation
Dessen P
RNF126 (ring finger protein 126)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/46757/rnf126
