Identity
HGNC
LOCATION
6p22.3
LOCUSID
ALIAS
IBRDC2,PIR2,bA528A10.3,p53RFP
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 255488
MIM: 618869
HGNC: 21578
Ensembl: ENSG00000137393
Variants:
dbSNP: 255488
ClinVar: 255488
TCGA: ENSG00000137393
COSMIC: RNF144B
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000137393 | ENST00000259939 | Q7Z419 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38685100 | 2024 | The TP53-activated E3 ligase RNF144B is a tumour suppressor that prevents genomic instability. | 0 |
| 38685100 | 2024 | The TP53-activated E3 ligase RNF144B is a tumour suppressor that prevents genomic instability. | 0 |
| 35699595 | 2022 | RNF144B stimulates the proliferation and inhibits the apoptosis of human spermatogonial stem cells via the FCER2/NOTCH2/HES1 pathway and its abnormality is associated with azoospermia. | 4 |
| 35699595 | 2022 | RNF144B stimulates the proliferation and inhibits the apoptosis of human spermatogonial stem cells via the FCER2/NOTCH2/HES1 pathway and its abnormality is associated with azoospermia. | 4 |
| 31509299 | 2019 | RNF144B inhibits LPS-induced inflammatory responses via binding TBK1. | 6 |
| 31509299 | 2019 | RNF144B inhibits LPS-induced inflammatory responses via binding TBK1. | 6 |
| 29724995 | 2018 | Pir2/Rnf144b is a potential endometrial cancer biomarker that promotes cell proliferation. | 6 |
| 29724995 | 2018 | Pir2/Rnf144b is a potential endometrial cancer biomarker that promotes cell proliferation. | 6 |
| 27524417 | 2017 | miR-100 antagonism triggers apoptosis by inhibiting ubiquitination-mediated p53 degradation. | 18 |
| 27524417 | 2017 | miR-100 antagonism triggers apoptosis by inhibiting ubiquitination-mediated p53 degradation. | 18 |
| 23128396 | 2013 | PIR2/Rnf144B regulates epithelial homeostasis by mediating degradation of p21WAF1 and p63. | 13 |
| 23128396 | 2013 | PIR2/Rnf144B regulates epithelial homeostasis by mediating degradation of p21WAF1 and p63. | 13 |
| 20300062 | 2010 | IBRDC2, an IBR-type E3 ubiquitin ligase, is a regulatory factor for Bax and apoptosis activation. | 42 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 20615966 | 2010 | Differential control of TAp73 and DeltaNp73 protein stability by the ring finger ubiquitin ligase PIR2. | 43 |
Citation
Dessen P
RNF144B (ring finger protein 144B)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/46739/rnf144b
