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RNF149 (ring finger protein 149)

Identity

Alias (NCBI)DNAPTP2
HGNC (Hugo) RNF149
HGNC Alias symbFLJ90504
LocusID (NCBI) 284996
Atlas_Id 47049
Location 2q11.2  [Link to chromosome band 2q11]
Location_base_pair Starts at 101275601 and ends at 101308701 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
RNF149 (2q11.2) / C1orf43 (1q21.3)RNF149 (2q11.2) / MYO6 (6q14.1)RNF149 (2q11.2) / PARP6 (15q23)
RNF149 (2q11.2) / RNF149 (2q11.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RNF149   23137
Cards
Entrez_Gene (NCBI)RNF149  284996  ring finger protein 149
AliasesDNAPTP2
GeneCards (Weizmann)RNF149
Ensembl hg19 (Hinxton)ENSG00000163162 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000163162 [Gene_View]  ENSG00000163162 [Sequence]  chr2:101275601-101308701 [Contig_View]  RNF149 [Vega]
ICGC DataPortalENSG00000163162
TCGA cBioPortalRNF149
AceView (NCBI)RNF149
Genatlas (Paris)RNF149
WikiGenes284996
SOURCE (Princeton)RNF149
Genetics Home Reference (NIH)RNF149
Genomic and cartography
GoldenPath hg38 (UCSC)RNF149  -     chr2:101275601-101308701 -  2q11.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RNF149  -     2q11.2   [Description]    (hg19-Feb_2009)
GoldenPathRNF149 - 2q11.2 [CytoView hg19]  RNF149 - 2q11.2 [CytoView hg38]
ImmunoBaseENSG00000163162
genome Data Viewer NCBIRNF149 [Mapview hg19]  
Gene and transcription
Genbank (Entrez)AK074985 AK075141 AK129799 AY450390 BC019355
RefSeq transcript (Entrez)NM_173647
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RNF149
Alternative Splicing GalleryENSG00000163162
Gene ExpressionRNF149 [ NCBI-GEO ]   RNF149 [ EBI - ARRAY_EXPRESS ]   RNF149 [ SEEK ]   RNF149 [ MEM ]
Gene Expression Viewer (FireBrowse)RNF149 [ Firebrowse - Broad ]
GenevisibleExpression of RNF149 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)284996
GTEX Portal (Tissue expression)RNF149
Human Protein AtlasENSG00000163162-RNF149 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NC42   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8NC42  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8NC42
Splice isoforms : SwissVarQ8NC42
Catalytic activity : Enzyme2.3.2.27 [ Enzyme-Expasy ]   2.3.2.272.3.2.27 [ IntEnz-EBI ]   2.3.2.27 [ BRENDA ]   2.3.2.27 [ KEGG ]   [ MEROPS ]
PhosPhoSitePlusQ8NC42
Domaine pattern : Prosite (Expaxy)ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)RNF149_RING-H2    Znf_RING    Znf_RING/FYVE/PHD   
Domain families : Pfam (Sanger)zf-RING_2 (PF13639)   
Domain families : Pfam (NCBI)pfam13639   
Domain families : Smart (EMBL)RING (SM00184)  
Conserved Domain (NCBI)RNF149
DMDM Disease mutations284996
Blocks (Seattle)RNF149
SuperfamilyQ8NC42
Human Protein Atlas [tissue]ENSG00000163162-RNF149 [tissue]
Peptide AtlasQ8NC42
HPRD11513
IPIIPI00175092   IPI00917006   
Protein Interaction databases
DIP (DOE-UCLA)Q8NC42
IntAct (EBI)Q8NC42
FunCoupENSG00000163162
BioGRIDRNF149
STRING (EMBL)RNF149
ZODIACRNF149
Ontologies - Pathways
QuickGOQ8NC42
Ontology : AmiGOcytoplasm  ubiquitin-dependent protein catabolic process  membrane  integral component of membrane  protein ubiquitination  regulation of protein stability  cellular response to drug  negative regulation of MAPK cascade  metal ion binding  ubiquitin protein ligase activity  
Ontology : EGO-EBIcytoplasm  ubiquitin-dependent protein catabolic process  membrane  integral component of membrane  protein ubiquitination  regulation of protein stability  cellular response to drug  negative regulation of MAPK cascade  metal ion binding  ubiquitin protein ligase activity  
NDEx NetworkRNF149
Atlas of Cancer Signalling NetworkRNF149
Wikipedia pathwaysRNF149
Orthology - Evolution
OrthoDB284996
GeneTree (enSembl)ENSG00000163162
Phylogenetic Trees/Animal Genes : TreeFamRNF149
HOGENOMQ8NC42
Homologs : HomoloGeneRNF149
Homology/Alignments : Family Browser (UCSC)RNF149
Gene fusions - Rearrangements
Fusion : QuiverRNF149
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRNF149 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RNF149
dbVarRNF149
ClinVarRNF149
1000_GenomesRNF149 
Exome Variant ServerRNF149
GNOMAD BrowserENSG00000163162
Varsome BrowserRNF149
Genetic variants : HAPMAP284996
Genomic Variants (DGV)RNF149 [DGVbeta]
DECIPHERRNF149 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRNF149 
Mutations
ICGC Data PortalRNF149 
TCGA Data PortalRNF149 
Broad Tumor PortalRNF149
OASIS PortalRNF149 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRNF149  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DRNF149
Mutations and Diseases : HGMDRNF149
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RNF149
DgiDB (Drug Gene Interaction Database)RNF149
DoCM (Curated mutations)RNF149 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RNF149 (select a term)
intoGenRNF149
Cancer3DRNF149(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETRNF149
MedgenRNF149
Genetic Testing Registry RNF149
NextProtQ8NC42 [Medical]
TSGene284996
GENETestsRNF149
Target ValidationRNF149
Huge Navigator RNF149 [HugePedia]
snp3D : Map Gene to Disease284996
BioCentury BCIQRNF149
ClinGenRNF149
Clinical trials, drugs, therapy
Protein Interactions : CTD284996
Pharm GKB GenePA134895641
Clinical trialRNF149
Miscellaneous
canSAR (ICR)RNF149 (select the gene name)
HarmonizomeRNF149
DataMed IndexRNF149
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRNF149
EVEXRNF149
GoPubMedRNF149
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Jul 16 15:33:40 CEST 2020

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